Literature DB >> 10985885

Gestational trophoblastic disease: a study of mode of evacuation and subsequent need for treatment with chemotherapy.

J A Tidy1, A M Gillespie, N Bright, C R Radstone, R E Coleman, B W Hancock.   

Abstract

OBJECTIVES: The aim of this study was to assess whether there was a change in the mode of evacuation of GTD over two time periods and to assess whether mode of evacuation influenced the subsequent need for chemotherapy.
METHODS: A retrospective case note study of 4257 cases between 1986 and 1996, at a screening and treatment center managing GTD, was performed.
RESULTS: Between the time periods 1986-1989 and 1990-1996 there was significant change in the mode of evacuation to suction curettage. The mode of evacuation was significant in determining the need for chemotherapy. The highest rate of chemotherapy was associated with medical methods of evacuation.
CONCLUSIONS: Suction curettage is a safe method of uterine evacuation in GTD and its usage has increased with time. Medical methods of uterine evacuation are associated with higher rates of chemotherapy. This is probably due to a higher rate of incomplete evacuation. Medical methods of evacuation should not be used in cases of complete hydatiform mole. Copyright 2000 Academic Press.

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Year:  2000        PMID: 10985885     DOI: 10.1006/gyno.2000.5839

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  14 in total

1.  Partial hydatidiform mole progression into invasive mole with lung metastasis following in vitro fertilization.

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2.  Medical termination of a partial hydatidiform mole and coexisting fetus during the second trimester: A case report.

Authors:  Yinfeng Wang; Honglang Qian; Jinhua Wang
Journal:  Oncol Lett       Date:  2015-09-24       Impact factor: 2.967

Review 3.  The role of surgery and radiation therapy in the management of gestational trophoblastic disease.

Authors:  Rabbie K Hanna; John T Soper
Journal:  Oncologist       Date:  2010-05-23

Review 4.  Gestational trophoblastic neoplasia: the management of relapsing patients and other recent advances.

Authors:  Naveed Sarwar; Edward S Newlands; Michael J Seckl
Journal:  Curr Oncol Rep       Date:  2004-11       Impact factor: 5.075

5.  Clinical presentation and treatment outcome of molar pregnancy: Ten years experience at a Tertiary Care Hospital in Dammam, Saudi Arabia.

Authors:  Ayman A Al-Talib
Journal:  J Family Community Med       Date:  2016 Sep-Dec

6.  Successful Primary Treatment of a Hydatidiform Mole with Methotrexate and EMA/CO.

Authors:  M De Vos; M Leunen; C Fontaine; Ph De Sutter
Journal:  Case Rep Med       Date:  2009-05-19

7.  Second Curettage for Low-Risk Nonmetastatic Gestational Trophoblastic Neoplasia.

Authors:  Raymond J Osborne; Virginia L Filiaci; Julian C Schink; Robert S Mannel; Kian Behbakht; James S Hoffman; Nick M Spirtos; John K Chan; John A Tidy; David S Miller
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8.  Gestational and Non-gestational Trophoblastic Disease. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry No. 032/049, December 2015).

Authors:  C Tempfer; L-C Horn; S Ackermann; M W Beckmann; R Dittrich; J Einenkel; A Günthert; H Haase; J Kratzsch; M C Kreissl; S Polterauer; A D Ebert; K T M Schneider; H G Strauss; F Thiel
Journal:  Geburtshilfe Frauenheilkd       Date:  2016-02       Impact factor: 2.915

9.  Transient Thyrotoxicosis in Molar Pregnancy.

Authors:  Samarth Virmani; Sujatha B Srinivas; Rama Bhat; Raghavendra Rao; Ranjini Kudva
Journal:  J Clin Diagn Res       Date:  2017-07-01

10.  Molar pregnancy after in vitro fertilization with euploid single embryo transfer.

Authors:  Beth Zhou; Helen Paige Anglin; Alexander M Quaas
Journal:  F S Rep       Date:  2021-01-22
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