Literature DB >> 10964377

Regioselective synthesis of 1,3,5-triaryl-4-alkylpyrazoles: novel ligands for the estrogen receptor.

Y R Huang1, J A Katzenellenbogen.   

Abstract

[reaction: see structure] A regioselective synthesis of 4-alkyl-1,3,5-triarylpyrazoles has been developed for the preparation of unsymmetrically substituted systems of interest as ligands for the estrogen receptor.

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Year:  2000        PMID： 10964377     DOI： 10.1021/ol0062650

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  13 in total

1.  Catalyst-free, one-pot, three-component synthesis of 5-amino-1,3-aryl-₁Η-pyrazole-4-carbonitriles in green media.

Authors:  Alireza Hasaninejad; Somayeh Firoozi
Journal:  Mol Divers       Date:  2013-04-27       Impact factor: 2.943

2.  Thermal electron-transfer-induced oxidation of 2-pyrazolines.

Authors:  Hamid Reza Memarian; Reza Minakar
Journal:  Mol Divers       Date:  2019-02-02       Impact factor: 2.943

Review 3.  Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review.

Authors:  Khalid Karrouchi; Smaail Radi; Youssef Ramli; Jamal Taoufik; Yahia N Mabkhot; Faiz A Al-Aizari; M'hammed Ansar
Journal:  Molecules       Date:  2018-01-12       Impact factor: 4.411

4.  A novel pseudo six-component synthesis of functionalized pyrazoles in ethanol by cascade reaction.

Authors:  Atieh Rezvanian; Maedeh Babashah; Maryam Anafcheh
Journal:  Mol Divers       Date:  2019-01-11       Impact factor: 2.943

5.  KSF: an efficient catalyst for the regioselective synthesis of 1,5-diaryl pyrazoles using Baylis-Hillman adducts.

Authors:  Mohammad Nikpassand; Manouchehr Mamaghani; Khalil Tabatabaeian; Maryam Kupaei Abiazi
Journal:  Mol Divers       Date:  2009-02-21       Impact factor: 2.943

6.  Synthesis and evaluation of 4-(substituted styryl/alkenyl)-3,5-bis(4-hydroxyphenyl)-isoxazoles as ligands for the estrogen receptor.

Authors:  Terra Haddad; Rachel Gershman; Robert Dilis; David Labaree; Richard B Hochberg; Robert N Hanson
Journal:  Bioorg Med Chem Lett       Date:  2012-07-15       Impact factor: 2.823

7.  Benzyl 5-ferrocenyl-3-(4-methyl-phen-yl)-2-pyrazoline-1-dithio-carboxyl-ate.

Authors:  Xiao-Lan Liu; Ben-Wan Tong; Yue Zhao; Jun Ye; Yong-Hong Liu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2007-12-18

8.  Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity.

Authors:  Hai-Bing Zhou; Kathryn E Carlson; Fabio Stossi; Benita S Katzenellenbogen; John A Katzenellenbogen
Journal:  Bioorg Med Chem Lett       Date:  2008-11-06       Impact factor: 2.823

9.  Copper triflate-mediated synthesis of 1,3,5-triarylpyrazoles in [bmim][PF6] ionic liquid and evaluation of their anticancer activities.

Authors:  V Kameshwara Rao; Rakesh Tiwari; Bhupender S Chhikara; Amir Nasrolahi Shirazi; Keykavous Parang; Anil Kumar
Journal:  RSC Adv       Date:  2013-09-21       Impact factor: 3.361

10.  Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins.

Authors:  Sirish K Ippagunta; Julie A Pollock; Naina Sharma; Wenwei Lin; Taosheng Chen; Kazuki Tawaratsumida; Anthony A High; Jaeki Min; Yizhe Chen; R Kiplin Guy; Vanessa Redecke; John A Katzenellenbogen; Hans Häcker
Journal:  Sci Signal       Date:  2018-08-14       Impact factor: 8.192
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