BACKGROUND: The purpose of this study was to evaluate the usefulness of computed tomographic (CT) fluoroscopy-guided transthoracic needle biopsy (TTNB) with an 18-gauge automatic biopsy gun for the diagnosis of pulmonary nodules. METHODS: Between March 1996 and January 1998, 50 patients in whom pulmonary lesions could not be diagnosed cytopathologically with fiberoptic bronchoscopy or were not clearly visualized with fluoroscopy underwent CT fluoroscopy-guided TTNB. RESULTS: Final pathological diagnoses were 23 lung carcinomas, five pulmonary metastases and 22 benign lesions. Sufficient tissue for analysis was obtained from 48 of the 50 lesions (96%). The overall diagnostic yield of CT fluoroscopy-guided TTNB was 90%. The sensitivity, specificity and accuracy for malignancy were 89%, 100% and 94%, respectively. In 20 of the 22 cases (91%) of benign lesions, histological analysis yielded correct and specific diagnoses. Complications occurred in 22 of the 50 cases (44%). The most common complication was pneumothorax, which occurred in 21 of the 50 cases (42%). Chest tube insertion was required in 6 (12%). CONCLUSIONS: Although CT fluoroscopy could not decrease the complication rate, CT fluoroscopy-guided TTNB with an automatic biopsy gun appears to be a promising technique for diagnosing pulmonary lesions, particularly benign lesions.
BACKGROUND: The purpose of this study was to evaluate the usefulness of computed tomographic (CT) fluoroscopy-guided transthoracic needle biopsy (TTNB) with an 18-gauge automatic biopsy gun for the diagnosis of pulmonary nodules. METHODS: Between March 1996 and January 1998, 50 patients in whom pulmonary lesions could not be diagnosed cytopathologically with fiberoptic bronchoscopy or were not clearly visualized with fluoroscopy underwent CT fluoroscopy-guided TTNB. RESULTS: Final pathological diagnoses were 23 lung carcinomas, five pulmonary metastases and 22 benign lesions. Sufficient tissue for analysis was obtained from 48 of the 50 lesions (96%). The overall diagnostic yield of CT fluoroscopy-guided TTNB was 90%. The sensitivity, specificity and accuracy for malignancy were 89%, 100% and 94%, respectively. In 20 of the 22 cases (91%) of benign lesions, histological analysis yielded correct and specific diagnoses. Complications occurred in 22 of the 50 cases (44%). The most common complication was pneumothorax, which occurred in 21 of the 50 cases (42%). Chest tube insertion was required in 6 (12%). CONCLUSIONS: Although CT fluoroscopy could not decrease the complication rate, CT fluoroscopy-guided TTNB with an automatic biopsy gun appears to be a promising technique for diagnosing pulmonary lesions, particularly benign lesions.
Authors: Christoph M Heyer; Stefan P Lemburg; Thomas Kagel; Klaus-Michael Mueller; Thomas G Nuesslein; Christian H L Rieger; Volkmar Nicolas Journal: Eur Radiol Date: 2005-01-26 Impact factor: 5.315
Authors: Ga Ram Kim; Jin Hur; Sang Min Lee; Hye-Jeong Lee; Yoo Jin Hong; Ji Eun Nam; Hua Sun Kim; Young Jin Kim; Byoung Wook Choi; Tae Hoon Kim; Kyu Ok Choe Journal: Eur Radiol Date: 2010-08-22 Impact factor: 5.315
Authors: Melissa K Accordino; Jason D Wright; Donna Buono; Alfred I Neugut; Dawn L Hershman Journal: J Oncol Pract Date: 2015-01-20 Impact factor: 3.840
Authors: Francis J Podbielski; Heron E Rodriguez; Andrew M Brown; Matthew J Blecha; Mario R Salazar; Mark M Connolly Journal: JSLS Date: 2004 Jul-Sep Impact factor: 2.172