Literature DB >> 109305

Ethanol metabolism in Drosophila melanogaster.

M C Deltombe-Lietaert, J Delcour, N Lenelle-Monfort, A Elens.   

Abstract

A quantitative study of the transformation of ethanol into acetaldehyde shows that, in Drosophila melanogaster, the mitochondrial ethanol oxidizing system is not very active but that the part played by catalase appears more important than expected. For a strain without alcoholdehydrogenase, ethanol is highly toxic. The presence of acetaldehyde in the culture medium is toxic for all the strains studied. But, since even a strain without any aldehydeoxidase lives normally, the metabolic production of acetaldehyde does not seem dangerous.

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Year:  1979        PMID： 109305     DOI： 10.1007/bf01960329

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  20 in total

1.  Microsomal ethanol oxidizing system (MEOS): current status of its characterization and its role.

Authors:  R Teschke; S Matsuzaki; K Ohnishi; L M DeCarli; C S Lieber
Journal:  Alcohol Clin Exp Res       Date:  1977-01       Impact factor: 3.455

2.  Effects of pyrazole and 3-amino-1,2,4-triazole on methanol and ethanol metabolism by the rat.

Authors:  E Feytmans; F Leighton
Journal:  Biochem Pharmacol       Date:  1973-02-01       Impact factor: 5.858

3.  Drosophila alcohol dehydrogenase. Purification and partial characterization.

Authors:  W Sofer; H Ursprung
Journal:  J Biol Chem       Date:  1968-06-10       Impact factor: 5.157

4.  Alterations of genetics material for analysis of alcohol dehydrogenase isozymes of Drosophila melanogaster.

Authors:  E H Grell; K B Jacobson; J B Murphy
Journal:  Ann N Y Acad Sci       Date:  1968-06-14       Impact factor: 5.691

5.  The contribution of ecological genetics to evolutionary theory: detecting the direct effects of natural selection on particular polymorphic loci.

Authors:  B Clarke
Journal:  Genetics       Date:  1975-06       Impact factor: 4.562

6.  Properties of genetically polymorphic isozymes of alcohol dehydrogenase in Drosophila melanogaster.

Authors:  T H Day; P C Hillier; B Clarke
Journal:  Biochem Genet       Date:  1974-02       Impact factor: 1.890

7.  [Genetic adaptation to ethanol: an important parameter in the evolution of geographic races of Drosophila melanogaster].

Authors:  J David; C Bocquet
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1974-10-14

8.  Polygenic control of aldehyde oxidase in Drosophila.

Authors:  J B Courtright
Journal:  Genetics       Date:  1967-09       Impact factor: 4.562

9.  Alcohol tolerance: An ecological parameter in the relative success of Drosophila melanogaster and Drosophila simulans.

Authors:  J A McKenzie; P A Parsons
Journal:  Oecologia       Date:  1972-12       Impact factor: 3.225

10.  Alcohol Dehydrogenase in Drosophila melanogaster: Isozymes and Genetic Variants.

Authors:  E H Grell; K B Jacobson; J B Murphy
Journal:  Science       Date:  1965-07-02       Impact factor: 47.728
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  8 in total

1.  Genetic divergence under uniform selection. II. Different responses to selection for knockdown resistance to ethanol among Drosophila melanogaster populations and their replicate lines.

Authors:  F M Cohan; A A Hoffmann
Journal:  Genetics       Date:  1986-09       Impact factor: 4.562

2.  Drosophila melanogaster aldehyde dehydrogenase.

Authors:  M C Liétaert; M Libion-Mannaert; S Wattiaux-De Coninck; A Elens
Journal:  Experientia       Date:  1985-01-15

3.  Larval behavioral response to environmental ethanol in relation to alcohol dehydrogenase activity level in Drosophila melanogaster.

Authors:  E Depiereux; N Hougouto; J Lechien; M Libion-Mannaert; M C Liétaert; E Feytmans; A Elens
Journal:  Behav Genet       Date:  1985-03       Impact factor: 2.805

Review 4.  Evolutionary genetics of the Drosophila alcohol dehydrogenase gene-enzyme system.

Authors:  P W Heinstra
Journal:  Genetica       Date:  1993       Impact factor: 1.082

5.  How can Drosophila flies without aldehyde oxidase detoxify acetaldehyde?

Authors:  M C Lietaert; M Libion-Mannaert; N Hougouto; A Elens
Journal:  Experientia       Date:  1982-06-15

6.  Chemical stimuli in host-habitat location byLeptopilina heterotoma (Thomson) (Hymenoptera: Eucoilidae), a parasite ofDrosophila.

Authors:  M Dicke; J C Van Lenteren; G J Boskamp; E van Dongen-van Leeuwen
Journal:  J Chem Ecol       Date:  1984-05       Impact factor: 2.626

7.  Dietary ethanol and lipid synthesis in Drosophila melanogaster.

Authors:  B W Geer; M L Langevin; S W McKechnie
Journal:  Biochem Genet       Date:  1985-08       Impact factor: 1.890

8.  Acetic acid vapour as a resource: threshold differences among three Drosophila species.

Authors:  P A Parsons
Journal:  Experientia       Date:  1980-12-15
  8 in total

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