Literature DB >> 10926173

The effects of acid on bone.

D A Bushinsky1, K K Frick.   

Abstract

Metabolic acidosis induces calcium efflux from bone and in the process buffers the additional hydrogen ions. Initially metabolic acidosis stimulates physicochemical mineral dissolution and then cell-mediated bone resorption. Acidosis increases activity of the bone resorbing cells, the osteoclasts, and decreases activity of the bone forming cells, the osteoblasts. Osteoblastic immediate early response genes are inhibited as are genes controlling matrix formation.

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Year:  2000        PMID： 10926173     DOI： 10.1097/00041552-200007000-00008

Source DB:  PubMed          Journal:  Curr Opin Nephrol Hypertens        ISSN： 1062-4821            Impact factor:   2.894


  27 in total

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2.  The Effect of a Whey Protein Supplement on Bone Mass in Older Caucasian Adults.

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Review 3.  The acid-ash hypothesis revisited: a reassessment of the impact of dietary acidity on bone.

Authors:  Rachel Nicoll; John McLaren Howard
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Journal:  Ann Rheum Dis       Date:  2018-07-30       Impact factor: 19.103

Review 5.  Incomplete Distal Renal Tubular Acidosis and Kidney Stones.

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Journal:  Adv Chronic Kidney Dis       Date:  2018-07       Impact factor: 3.620

6.  Assessment and treatment of short stature in pediatric patients with chronic kidney disease: a consensus statement.

Authors:  John D Mahan; Bradley A Warady
Journal:  Pediatr Nephrol       Date:  2006-05-30       Impact factor: 3.714

7.  Stature in children with chronic kidney disease: analysis of NAPRTCS database.

Authors:  Mouin G Seikaly; Nina Salhab; Debbie Gipson; Verna Yiu; Donald Stablein
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8.  Supplementing a low-protein diet with dibasic amino acids increases urinary calcium excretion in young women.

Authors:  Jessica D Bihuniak; Rebecca R Sullivan; Christine A Simpson; Donna M Caseria; Tania B Huedo-Medina; Kimberly O O'Brien; Jane E Kerstetter; Karl L Insogna
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Review 9.  [Pharmaceutical therapy of bone metabolism disorders in chronic kidney disease mineral bone disorder (CKD-MBD) with special respect to antiresorptive substances].

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Journal:  Z Rheumatol       Date:  2014-05       Impact factor: 1.372

Review 10.  Acidosis and Urinary Calcium Excretion: Insights from Genetic Disorders.

Authors:  R Todd Alexander; Emmanuelle Cordat; Régine Chambrey; Henrik Dimke; Dominique Eladari
Journal:  J Am Soc Nephrol       Date:  2016-07-28       Impact factor: 10.121
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