Literature DB >> 27468975

Acidosis and Urinary Calcium Excretion: Insights from Genetic Disorders.

R Todd Alexander1,2, Emmanuelle Cordat2, Régine Chambrey3, Henrik Dimke4, Dominique Eladari3,5.   

Abstract

Metabolic acidosis is associated with increased urinary calcium excretion and related sequelae, including nephrocalcinosis and nephrolithiasis. The increased urinary calcium excretion induced by metabolic acidosis predominantly results from increased mobilization of calcium out of bone and inhibition of calcium transport processes within the renal tubule. The mechanisms whereby acid alters the integrity and stability of bone have been examined extensively in the published literature. Here, after briefly reviewing this literature, we consider the effects of acid on calcium transport in the renal tubule and then discuss why not all gene defects that cause renal tubular acidosis are associated with hypercalciuria and nephrocalcinosis.
Copyright © 2016 by the American Society of Nephrology.

Entities:  

Keywords:  calcium; chronic metabolic acidosis; hypercalciuria; renal tubular acidosis

Mesh：

Substances：

Year:  2016        PMID： 27468975      PMCID： PMC5118493          DOI： 10.1681/ASN.2016030305

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN： 1046-6673            Impact factor:   10.121


  132 in total

1.  EFFECT OF VARIATIONS IN SODIUM INTAKE ON CALCIUM EXCRETION IN NORMAL HUMANS.

Authors:  C R KLEEMAN; J BOHANNAN; D BERNSTEIN; S LING; M H MAXWELL
Journal:  Proc Soc Exp Biol Med       Date:  1964-01

2.  Extracellular pH dynamically controls cell surface delivery of functional TRPV5 channels.

Authors:  Tim T Lambers; Elena Oancea; Theun de Groot; Catalin N Topala; Joost G Hoenderop; René J Bindels
Journal:  Mol Cell Biol       Date:  2006-12-18       Impact factor: 4.272

3.  Novel ATP6V1B1 and ATP6V0A4 mutations in autosomal recessive distal renal tubular acidosis with new evidence for hearing loss.

Authors:  E H Stover; K J Borthwick; C Bavalia; N Eady; D M Fritz; N Rungroj; A B S Giersch; C C Morton; P R Axon; I Akil; E A Al-Sabban; D M Baguley; S Bianca; A Bakkaloglu; Z Bircan; D Chauveau; M-J Clermont; A Guala; S A Hulton; H Kroes; G Li Volti; S Mir; H Mocan; A Nayir; S Ozen; J Rodriguez Soriano; S A Sanjad; V Tasic; C M Taylor; R Topaloglu; A N Smith; F E Karet
Journal:  J Med Genet       Date:  2002-11       Impact factor: 6.318

4.  Renal intercalated cells are rather energized by a proton than a sodium pump.

Authors:  Régine Chambrey; Ingo Kurth; Janos Peti-Peterdi; Pascal Houillier; Jeffrey M Purkerson; Françoise Leviel; Moritz Hentschke; Anselm A Zdebik; George J Schwartz; Christian A Hübner; Dominique Eladari
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-22       Impact factor: 11.205

5.  Effect of metabolic acidosis on the potassium content of bone.

Authors:  D A Bushinsky; K Gavrilov; J M Chabala; J D Featherstone; R Levi-Setti
Journal:  J Bone Miner Res       Date:  1997-10       Impact factor: 6.741

6.  Report of a family with two different hereditary diseases leading to early nephrocalcinosis.

Authors:  Rosa Vargas-Poussou; Pierre Cochat; Nelly Le Pottier; Isabelle Roncelin; Aurelia Liutkus; Anne Blanchard; Xavier Jeunemaître
Journal:  Pediatr Nephrol       Date:  2007-09-26       Impact factor: 3.714

7.  Renal phenotype in Lowe Syndrome: a selective proximal tubular dysfunction.

Authors:  Detlef Bockenhauer; Arend Bokenkamp; William van't Hoff; Elena Levtchenko; Joana E Kist-van Holthe; Velibor Tasic; Michael Ludwig
Journal:  Clin J Am Soc Nephrol       Date:  2008-05-14       Impact factor: 8.237

8.  Persistent isolated proximal renal tubular acidosis--a systemic disease with a distinct clinical entity.

Authors:  T Igarashi; T Ishii; K Watanabe; H Hayakawa; K Horio; Y Sone; K Ohga
Journal:  Pediatr Nephrol       Date:  1994-02       Impact factor: 3.714

9.  The Vacuolar H+-ATPase B1 Subunit Polymorphism p.E161K Associates with Impaired Urinary Acidification in Recurrent Stone Formers.

Authors:  Nasser A Dhayat; Andre Schaller; Giuseppe Albano; John Poindexter; Carolyn Griffith; Andreas Pasch; Sabina Gallati; Bruno Vogt; Orson W Moe; Daniel G Fuster
Journal:  J Am Soc Nephrol       Date:  2015-10-09       Impact factor: 10.121

10.  Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex.

Authors:  Jianghui Hou; Aparna Renigunta; Martin Konrad; Antonio S Gomes; Eveline E Schneeberger; David L Paul; Siegfried Waldegger; Daniel A Goodenough
Journal:  J Clin Invest       Date:  2008-02       Impact factor: 14.808
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  13 in total

Review 1.  Incomplete Distal Renal Tubular Acidosis and Kidney Stones.

Authors:  Daniel G Fuster; Orson W Moe
Journal:  Adv Chronic Kidney Dis       Date:  2018-07       Impact factor: 3.620

Review 2.  Nephrolithiasis secondary to inherited defects in the thick ascending loop of henle and connecting tubules.

Authors:  Nicolas Faller; Nasser A Dhayat; Daniel G Fuster
Journal:  Urolithiasis       Date:  2018-11-20       Impact factor: 3.436

3.  Hearing loss without overt metabolic acidosis in ATP6V1B1 deficient MRL mice, a new genetic model for non-syndromic deafness with enlarged vestibular aqueducts.

Authors:  Cong Tian; Leona H Gagnon; Chantal Longo-Guess; Ron Korstanje; Susan M Sheehan; Kevin K Ohlemiller; Angela D Schrader; Jaclynn M Lett; Kenneth R Johnson
Journal:  Hum Mol Genet       Date:  2017-10-01       Impact factor: 6.150

4.  A clinical approach to tubulopathies in children and young adults.

Authors:  Andrew Mallett; Hugh McCarthy; Rachael Kermond
Journal:  Pediatr Nephrol       Date:  2022-05-18       Impact factor: 3.714

5.  Living-donor kidney transplantation for a patient with hypoparathyroidism, deafness, and renal dysplasia syndrome.

Authors:  Nobutaka Nishimura; Shunta Hori; Chihiro Omori; Makito Miyake; Satoshi Anai; Kazumasa Torimoto; Katsuya Aoki; Nobumichi Tanaka; Tatsuo Yoneda; Kiyohide Fujimoto
Journal:  IJU Case Rep       Date:  2020-07-27

6.  Molecular aspects and long-term outcome of patients with primary distal renal tubular acidosis.

Authors:  Sara Gómez-Conde; Alejandro García-Castaño; Mireia Aguirre; María Herrero; Leire Gondra; Nélida García-Pérez; Paula García-Ledesma; Luis Martín-Penagos; Cecilia Dall'Anese; Gema Ariceta; Luis Castaño; Leire Madariaga
Journal:  Pediatr Nephrol       Date:  2021-04-21       Impact factor: 3.714

Review 7.  Molecular mechanisms altering tubular calcium reabsorption.

Authors:  Mallory L Downie; R Todd Alexander
Journal:  Pediatr Nephrol       Date:  2021-04-01       Impact factor: 3.714

8.  Red Blood Cell AE1/Band 3 Transports in Dominant Distal Renal Tubular Acidosis Patients.

Authors:  Jean-Philippe Bertocchio; Sandrine Genetet; Lydie Da Costa; Stephen B Walsh; Bertrand Knebelmann; Julie Galimand; Lucie Bessenay; Corinne Guitton; Renaud De Lafaille; Rosa Vargas-Poussou; Dominique Eladari; Isabelle Mouro-Chanteloup
Journal:  Kidney Int Rep       Date:  2020-01-13

9.  Comparison of fractional excretion of electrolytes in patients at different stages of chronic kidney disease: A cross-sectional study.

Authors:  Po-Jen Hsiao; Chen-Yi Liao; Yung-Hsi Kao; Jenq-Shyong Chan; Yuh-Feng Lin; Chih-Pin Chuu; Jin-Shuen Chen
Journal:  Medicine (Baltimore)       Date:  2020-01       Impact factor: 1.817

10.  Hypertonic saline-induced urolithiasis presenting as acute renal failure in a child with traumatic brain injury: A case report.

Authors:  Jasper Bash; Sarah Hecht; Aaron Bayne; Casey Seideman
Journal:  Urol Case Rep       Date:  2020-10-30
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