| Literature DB >> 10925175 |
P G Simos1, J I Breier, J M Fletcher, B R Foorman, E Bergman, K Fishbeck, A C Papanicolaou.
Abstract
The purpose of the study was to identify spatiotemporal brain activation profiles associated with phonological decoding in dyslexic children using magnetic source imaging. For this purpose maps of regional cerebral activation were obtained from eleven children diagnosed with dyslexia and ten children without reading problems during engagement in a pseudoword rhyme-matching task. All dyslexic children showed aberrant activation maps consisting of reduced activity in temporoparietal areas in the left hemisphere (including the posterior part of the superior temporal, angular and supramarginal gyri) and increased activity in the right homotopic region. In contrast, the two groups of children did not differ in the degree of activity in basal temporal areas that typically precedes temporoparietal activation. This is the first study to demonstrate the existence of distinct activation profiles associated with phonological decoding in individual dyslexic children.Entities:
Mesh：
Year: 2000 PMID： 10925175 DOI： 10.1016/s0304-3940(00)01322-7
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046