Literature DB >> 10916158

Alternative pre-mRNA splicing: the logic of combinatorial control.

C W Smith1, J Valcárcel.   

Abstract

Alternative splicing of mRNA precursors is a versatile mechanism of gene expression regulation that accounts for a considerable proportion of proteomic complexity in higher eukaryotes. Its modulation is achieved through the combinatorial interplay of positive and negative regulatory signals present in the RNA, which are recognized by complexes composed of members of the hnRNP and SR protein families.

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Year:  2000        PMID： 10916158     DOI： 10.1016/s0968-0004(00)01604-2

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  354 in total

1.  SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs.

Authors:  A Sureau; R Gattoni; Y Dooghe; J Stévenin; J Soret
Journal:  EMBO J       Date:  2001-04-02       Impact factor: 11.598

2.  Gene2EST: a BLAST2 server for searching expressed sequence tag (EST) databases with eukaryotic gene-sized queries.

Authors:  C Gemünd; C Ramu; B Altenberg-Greulich; T J Gibson
Journal:  Nucleic Acids Res       Date:  2001-03-15       Impact factor: 16.971

3.  Alternative splicing of U12-dependent introns in vivo responds to purine-rich enhancers.

Authors:  R C Dietrich; G C Shukla; J D Fuller; R A Padgett
Journal:  RNA       Date:  2001-10       Impact factor: 4.942

4.  The KH-type RNA-binding protein PSI is required for Drosophila viability, male fertility, and cellular mRNA processing.

Authors:  Emmanuel Labourier; Marco Blanchette; Jennie W Feiger; Melissa D Adams; Donald C Rio
Journal:  Genes Dev       Date:  2002-01-01       Impact factor: 11.361

5.  In vitro selection of exonic splicing enhancer sequences: identification of novel CD44 enhancers.

Authors:  G Woerfel; A Bindereif
Journal:  Nucleic Acids Res       Date:  2001-08-01       Impact factor: 16.971

6.  Genome-wide detection of alternative splicing in expressed sequences of human genes.

Authors:  B Modrek; A Resch; C Grasso; C Lee
Journal:  Nucleic Acids Res       Date:  2001-07-01       Impact factor: 16.971

7.  PALS db: Putative Alternative Splicing database.

Authors:  Y-H Huang; Y-T Chen; J-J Lai; S-T Yang; U-C Yang
Journal:  Nucleic Acids Res       Date:  2002-01-01       Impact factor: 16.971

Review 8.  RNA-protein interactions that regulate pre-mRNA splicing.

Authors:  Ravinder Singh
Journal:  Gene Expr       Date:  2002

9.  Mutational analysis of a plant branchpoint and polypyrimidine tract required for constitutive splicing of a mini-exon.

Authors:  Craig G Simpson; Graham Thow; Gillian P Clark; S Nikki Jennings; Jenny A Watters; John W S Brown
Journal:  RNA       Date:  2002-01       Impact factor: 4.942

10.  The hnRNP A1 protein regulates HIV-1 tat splicing via a novel intron silencer element.

Authors:  T O Tange; C K Damgaard; S Guth; J Valcárcel; J Kjems
Journal:  EMBO J       Date:  2001-10-15       Impact factor: 11.598
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