Literature DB >> 10889319

Synthesis and antispasmodic activity of analogues of natural pterosins.

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Abstract

The synthesis of an extensive range of analogues of natural pterosins using modified Heck coupling is reported. The smooth muscle relaxant activity of these compounds has been examimed. Several compounds with significant smooth muscle relaxant activity have been identified.

Entities:  

Year:  1999        PMID： 10889319     DOI： 10.1016/s0223-5234(99)00113-0

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  7 in total

Review 1.  Twenty-first century mast cell stabilizers.

Authors:  D F Finn; J J Walsh
Journal:  Br J Pharmacol       Date:  2013-09       Impact factor: 8.739

2.  N-Cyclo-pentyl-N-(3-oxo-2,3-dihydro-1H-inden-1-yl)acetamide.

Authors:  Tao Zhang; Tom McCabe; Bartosz Marzec; Neil Frankish; Helen Sheridan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-03-03

3.  Molecular structure studies of (1S,2S)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol.

Authors:  Tao Zhang; Krzysztof Paluch; Gaia Scalabrino; Neil Frankish; Anne-Marie Healy; Helen Sheridan
Journal:  J Mol Struct       Date:  2015-03-05       Impact factor: 3.196

4.  Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A.

Authors:  Kit Chan; Neil Frankish; Tao Zhang; Abdulilah Ece; Aoife Cannon; Jacintha O'Sullivan; Helen Sheridan
Journal:  J Pharm Pharmacol       Date:  2020-04-16       Impact factor: 3.765

5.  2-(Di-phenyl-methyl-idene)-2,3-di-hydro-1H-inden-1-one.

Authors:  Tao Zhang; Vilmar Bandero; Tom McCabe; Neil Frankish; Helen Sheridan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-07-24

6.  The indane diastereoisomers, PH2 and PH5: divergence between their effects in delayed-type hypersensitivity models and a model of colitis.

Authors:  Neil H Frankish; Brendan McHale; Helen Sheridan
Journal:  J Pharm Pharmacol       Date:  2017-10-23       Impact factor: 3.765

7.  Bioactive Indanes: Proof of Concept Study for Enantioselective Synthetic Routes to PH46A, a New Potential Anti-Inflammatory Agent.

Authors:  Tao Zhang; Gaia Scalabrino; Neil Frankish; Helen Sheridan
Journal:  Molecules       Date:  2018-06-21       Impact factor: 4.411
  7 in total

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