T Kinoshita1, T Okudera, H Tamura, T Ogawa, J Hatazawa. 1. Department of Radiology, Research Institute of Brain and Blood Vessels-Akita, Akita, Japan. kino2grape.med.tottori-u.ac.jp
Abstract
BACKGROUND AND PURPOSE: Echo-planar gradient-echo T2*-weighted MR imaging (GRE-EPI) may detect hypointense lesions representing microhemorrhages with high sensitivity. The aim of this study was to evaluate the effectiveness of GRE-EPI for detecting old lacunar hemorrhages in hypertensive patients with stroke. METHODS: GRE-EPI was performed with a 1.5-T MRI system in 198 hypertensive patients with stroke (130 patients with hemorrhagic stroke and 68 patients with multiple lacunar stroke) and 66 age-matched healthy elderly individuals. RESULTS: Concomitant hypointense foci were found in 84 (66%) patients with hemorrhagic stroke, 46 (68%) patients with multiple lacunar stroke, and 3 (5%) healthy elderly individuals. These hypointense foci were noted in the lentiform nucleus in 61 (47%) patients with hemorrhagic stroke, in the caudate nucleus in 9 (7%) patients, in the thalamus in 54 (42%) patients, in the corticosubcortical region in 57 (44%) patients, in the brain stem in 40 (34%) patients, and in the cerebellum in 32 (25%) patients. CONCLUSIONS: GRE-EPI is effective for the detection of lacunar hemorrhages induced by hypertension.
BACKGROUND AND PURPOSE: Echo-planar gradient-echo T2*-weighted MR imaging (GRE-EPI) may detect hypointense lesions representing microhemorrhages with high sensitivity. The aim of this study was to evaluate the effectiveness of GRE-EPI for detecting old lacunar hemorrhages in hypertensivepatients with stroke. METHODS: GRE-EPI was performed with a 1.5-T MRI system in 198 hypertensivepatients with stroke (130 patients with hemorrhagic stroke and 68 patients with multiple lacunar stroke) and 66 age-matched healthy elderly individuals. RESULTS: Concomitant hypointense foci were found in 84 (66%) patients with hemorrhagic stroke, 46 (68%) patients with multiple lacunar stroke, and 3 (5%) healthy elderly individuals. These hypointense foci were noted in the lentiform nucleus in 61 (47%) patients with hemorrhagic stroke, in the caudate nucleus in 9 (7%) patients, in the thalamus in 54 (42%) patients, in the corticosubcortical region in 57 (44%) patients, in the brain stem in 40 (34%) patients, and in the cerebellum in 32 (25%) patients. CONCLUSIONS: GRE-EPI is effective for the detection of lacunar hemorrhages induced by hypertension.
Authors: Rainer Scheid; Cristoph Preul; Oliver Gruber; Christopher Wiggins; D Yves von Cramon Journal: AJNR Am J Neuroradiol Date: 2003 Jun-Jul Impact factor: 3.825
Authors: Robert N Peck; Ethan Green; Jacob Mtabaji; Charles Majinge; Luke R Smart; Jennifer A Downs; Daniel W Fitzgerald Journal: J Hypertens Date: 2013-09 Impact factor: 4.844