Robert N Peck1, Ethan Green, Jacob Mtabaji, Charles Majinge, Luke R Smart, Jennifer A Downs, Daniel W Fitzgerald. 1. aDepartment of Medicine, Bugando Medical Centre, Mwanza bDepartment of Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania cCenter for Global Health, Weill Cornell Medical College, New York dCornell University, Ithaca, New York, USA eDepartment of Physiology, Weill Bugando School of Medicine fDirector General, Bugando Medical Centre, Mwanza, Tanzania.
Abstract
OBJECTIVE: Hypertension is believed to be an increasingly common driver of the epidemic of noncommunicable diseases (NCDs) in sub-Saharan Africa, but prospective data are scarce. The objective of this prospective study was to determine the contribution of hypertension to deaths, admissions, and hospital days at a Tanzanian zonal hospital. METHODS: Between 2009 and 2011, diagnoses were recorded for all medical admissions together with age, sex, length of hospitalization and in-hospital mortality. RESULTS: Among 11045 consecutive admissions, NCDs accounted for nearly half of all deaths, admissions, and hospital days. Among NCDs, hypertension-related diseases were the most common and accounted for 314 (33.9%) of the total NCD deaths, 1611 (29.9%) of the NCD admissions, and 12837 (27.8%) NCD hospital days. Stroke (167 deaths) was the leading cause of hypertension-related death. Hypertension was the leading cause of death in patients over the age of 50 years and 57% of hypertension-related deaths occurred in patients less than 65 years old. CONCLUSION: NCDs account for half of all deaths, admissions and hospital days at our Tanzanian hospital and hypertension-related diseases were the most common NCD. Hypertension accounted for 34% of NCD deaths and 15% of all deaths. Hypertension was the second most common cause of death overall and the leading cause of death in patients more than 50 years old. More than half of hypertension-related deaths occurred before retirement age. These findings have important implications for public health and medical education in sub-Saharan Africa, wherein hypertension and related diseases have not traditionally been given a high priority.
OBJECTIVE:Hypertension is believed to be an increasingly common driver of the epidemic of noncommunicable diseases (NCDs) in sub-Saharan Africa, but prospective data are scarce. The objective of this prospective study was to determine the contribution of hypertension to deaths, admissions, and hospital days at a Tanzanian zonal hospital. METHODS: Between 2009 and 2011, diagnoses were recorded for all medical admissions together with age, sex, length of hospitalization and in-hospital mortality. RESULTS: Among 11045 consecutive admissions, NCDs accounted for nearly half of all deaths, admissions, and hospital days. Among NCDs, hypertension-related diseases were the most common and accounted for 314 (33.9%) of the total NCD deaths, 1611 (29.9%) of the NCD admissions, and 12837 (27.8%) NCD hospital days. Stroke (167 deaths) was the leading cause of hypertension-relateddeath. Hypertension was the leading cause of death in patients over the age of 50 years and 57% of hypertension-related deaths occurred in patients less than 65 years old. CONCLUSION: NCDs account for half of all deaths, admissions and hospital days at our Tanzanian hospital and hypertension-related diseases were the most common NCD. Hypertension accounted for 34% of NCD deaths and 15% of all deaths. Hypertension was the second most common cause of death overall and the leading cause of death in patients more than 50 years old. More than half of hypertension-related deaths occurred before retirement age. These findings have important implications for public health and medical education in sub-Saharan Africa, wherein hypertension and related diseases have not traditionally been given a high priority.
Authors: Bongani M Mayosi; Alan J Flisher; Umesh G Lalloo; Freddy Sitas; Stephen M Tollman; Debbie Bradshaw Journal: Lancet Date: 2009-08-24 Impact factor: 79.321
Authors: M Njelekela; H Negishi; Y Nara; M Tomohiro; S Kuga; T Noguchi; T Kanda; M Yamori; Y Mashalla; L Jian Liu; J Mtabaji; K Ikeda; Y Yamori Journal: Acta Trop Date: 2001-06-22 Impact factor: 3.112
Authors: P Pauletto; M Puato; M G Caroli; E Casiglia; A E Munhambo; G Cazzolato; G Bittolo Bon; M T Angeli; C Galli; A C Pessina Journal: Lancet Date: 1996-09-21 Impact factor: 79.321
Authors: Aram V Chobanian; George L Bakris; Henry R Black; William C Cushman; Lee A Green; Joseph L Izzo; Daniel W Jones; Barry J Materson; Suzanne Oparil; Jackson T Wright; Edward J Roccella Journal: Hypertension Date: 2003-12-01 Impact factor: 10.190
Authors: Bahati Mk Wajanga; Samuel Kalluvya; Jennifer A Downs; Warren D Johnson; Daniel W Fitzgerald; Robert N Peck Journal: J Int AIDS Soc Date: 2011-10-11 Impact factor: 5.396
Authors: Marleen E Hendriks; Ferdinand W N M Wit; Marijke T L Roos; Lizzy M Brewster; Tanimola M Akande; Ingrid H de Beer; Sayoki G Mfinanga; Amos M Kahwa; Peter Gatongi; Gert Van Rooy; Wendy Janssens; Judith Lammers; Berber Kramer; Igna Bonfrer; Esegiel Gaeb; Jacques van der Gaag; Tobias F Rinke de Wit; Joep M A Lange; Constance Schultsz Journal: PLoS One Date: 2012-03-12 Impact factor: 3.240
Authors: Anthony C Liwa; Luke R Smart; Amara Frumkin; Helen-Ann B Epstein; Daniel W Fitzgerald; Robert N Peck Journal: Curr Hypertens Rep Date: 2014-06 Impact factor: 5.369
Authors: Julian T Hertz; Francis M Sakita; Preeti Manavalan; Deng B Madut; Nathan M Thielman; Blandina T Mmbaga; Catherine A Staton; Sophie W Galson Journal: Ethn Dis Date: 2019-10-17 Impact factor: 1.847
Authors: Robert N Peck; Richard J Wang; Graham Mtui; Luke Smart; Missana Yango; Rim Elchaki; Bahati Wajanga; Jennifer A Downs; Kien Mteta; Daniel W Fitzgerald Journal: J Acquir Immune Defic Syndr Date: 2016-12-15 Impact factor: 3.731
Authors: Mjs Muchanga; F B Lepira; R Tozin; E P Mbelambela; N R Ngatu; E K Sumaili; J R Makulo; N Suganuma Journal: Afr Health Sci Date: 2016-12 Impact factor: 0.927
Authors: Justin R Kingery; Missana Yango; Bahati Wajanga; Fredrick Kalokola; Josef Brejt; Johannes Kataraihya; Robert Peck Journal: Int J Cardiol Date: 2017-05-09 Impact factor: 4.164
Authors: Laura D Sander; Kevin Newell; Paschal Ssebbowa; David Serwadda; Thomas C Quinn; Ronald H Gray; Maria J Wawer; George Mondo; Steven Reynolds Journal: Trop Med Int Health Date: 2014-12-26 Impact factor: 2.622
Authors: John Maginga; Mariana Guerrero; Eileen Koh; Christian Holm Hansen; Rehema Shedafa; Fredrick Kalokola; Luke R Smart; Robert N Peck Journal: J Clin Hypertens (Greenwich) Date: 2015-08-17 Impact factor: 3.738
Authors: Karl G Reis; Raymond Wilson; Fredrick Kalokola; Bahati Wajanga; Myung-Hee Lee; Monika Safford; Robert N Peck Journal: Am J Hypertens Date: 2020-12-31 Impact factor: 3.080
Authors: Alfred J Meremo; Matobogolo B Masalu; Issa Sabi; David P Ngilangwa; Janet Kapinga; Rehema Tagalile; Mariam J Munyogwa; Masumbuko Y Mwashambwa Journal: East Afr Health Res J Date: 2018-04-01