Literature DB >> 10878085

Survey for the presence and distribution of human herpesvirus 8 in healthy brain.

P K Chan1, H K Ng, J L Cheung, A F Cheng.   

Abstract

Brain tissues from both sides of the cerebellum and frontal, temporal, parietal, and occipital lobes were collected postmortem from 30 patients for human herpesvirus 8 (HHV-8) detection by PCR. Overall, 42 of 300 (14.0%) samples were positive, with similar rates for each position. Nineteen patients (63.3%) were positive and showed a significant increase in positivity with age (P = 0.007). The results indicate a neuroinvasive and neuropersistent potential of HHV-8.

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Year:  2000        PMID: 10878085      PMCID: PMC87028     

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  15 in total

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