Literature DB >> 7997879

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma.

Y Chang1, E Cesarman, M S Pessin, F Lee, J Culpepper, D M Knowles, P S Moore.   

Abstract

Representational difference analysis was used to isolate unique sequences present in more than 90 percent of Kaposi's sarcoma (KS) tissues obtained from patients with acquired immunodeficiency syndrome (AIDS). These sequences were not present in tissue DNA from non-AIDS patients, but were present in 15 percent of non-KS tissue DNA samples from AIDS patients. The sequences are homologous to, but distinct from, capsid and tegument protein genes of the Gammaherpesvirinae, herpesvirus saimiri and Epstein-Barr virus. These KS-associated herpesvirus-like (KSHV) sequences appear to define a new human herpesvirus.

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Year:  1994        PMID： 7997879     DOI： 10.1126/science.7997879

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  1773 in total

1.  Identification of human herpesvirus 8-specific cytotoxic T-cell responses.

Authors:  M Osman; T Kubo; J Gill; F Neipel; M Becker; G Smith; R Weiss; B Gazzard; C Boshoff; F Gotch
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

2.  Identification and rapid quantification of early- and late-lytic human herpesvirus 8 infection in single cells by flow cytometric analysis: characterization of antiherpesvirus agents.

Authors:  J P Zoeteweij; S T Eyes; J M Orenstein; T Kawamura; L Wu; B Chandran; B Forghani; A Blauvelt
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

3.  Identification of the immediate-early transcripts of Kaposi's sarcoma-associated herpesvirus.

Authors:  F X Zhu; T Cusano; Y Yuan
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

4.  A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi's sarcoma-associated herpesvirus.

Authors:  R Sadler; L Wu; B Forghani; R Renne; W Zhong; B Herndier; D Ganem
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

5.  Correlation between enzyme-linked immunosorbent assay and immunofluorescence assay with lytic antigens for detection of antibodies to human herpesvirus 8.

Authors:  S Topino; L Vincenzi; I Mezzaroma; E Nicastri; M Andreoni; M C Sirianni
Journal:  Clin Diagn Lab Immunol       Date:  2001-01

6.  Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays.

Authors:  R G Jenner; M M Albà; C Boshoff; P Kellam
Journal:  J Virol       Date:  2001-01       Impact factor: 5.103

7.  Risk of HIV related Kaposi's sarcoma and non-Hodgkin's lymphoma with potent antiretroviral therapy: prospective cohort study. Swiss HIV Cohort Study.

Authors:  B Ledergerber; A Telenti; M Egger
Journal:  BMJ       Date:  1999-07-03

Review 8.  Convicting a human tumor virus: guilt by association?

Authors:  J A Blaho; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

9.  Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins.

Authors:  S Ishido; C Wang; B S Lee; G B Cohen; J U Jung
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

10.  Characterization of two divergent lineages of macaque rhadinoviruses related to Kaposi's sarcoma-associated herpesvirus.

Authors:  E R Schultz; G W Rankin; M P Blanc; B W Raden; C C Tsai; T M Rose
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103
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