Literature DB >> 10867704

Evaluation of carrier agents for hyperpolarized xenon MRI.

A K Venkatesh1, L Zhao, D Balamore, F A Jolesz, M S Albert.   

Abstract

Several biocompatible carrier agents, in which xenon is highly soluble and has a long T(1), were tested, and injected in living rats. These included saline, Intralipid suspension, perfluorocarbon emulsion and (129)Xe gas-filled liposomes. The T(1) of (129)Xe in these compounds ranged from 47 to 116 s. Vascular injection of these carrier agents was tolerated well, encouraging their use for further experiments in live animals. In vivo spectra, obtained from gas-filled liposomes and perfluorocarbon solutions, suggest that these carrier agents have potential for use in angiography and perfusion imaging. Copyright 2000 John Wiley & Sons, Ltd.

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Keywords:  NASA Discipline Life Sciences Technologies; Non-NASA Center

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Year:  2000        PMID: 10867704     DOI: 10.1002/1099-1492(200006)13:4<245::aid-nbm635>3.0.co;2-7

Source DB:  PubMed          Journal:  NMR Biomed        ISSN: 0952-3480            Impact factor:   4.044


  7 in total

1.  XeNA: an automated 'open-source' (129)Xe hyperpolarizer for clinical use.

Authors:  Panayiotis Nikolaou; Aaron M Coffey; Laura L Walkup; Brogan M Gust; Nicholas Whiting; Hayley Newton; Iga Muradyan; Mikayel Dabaghyan; Kaili Ranta; Gregory D Moroz; Matthew S Rosen; Samuel Patz; Michael J Barlow; Eduard Y Chekmenev; Boyd M Goodson
Journal:  Magn Reson Imaging       Date:  2014-02-10       Impact factor: 2.546

2.  Measurements of the persistent singlet state of N2O in blood and other solvents--potential as a magnetic tracer.

Authors:  R K Ghosh; S J Kadlecek; J H Ardenkjaer-Larsen; B M Pullinger; G Pileio; M H Levitt; N N Kuzma; R R Rizi
Journal:  Magn Reson Med       Date:  2011-10       Impact factor: 4.668

Review 3.  Blood substitutes: evolution from noncarrying to oxygen- and gas-carrying fluids.

Authors:  Pedro Cabrales; Marcos Intaglietta
Journal:  ASAIO J       Date:  2013 Jul-Aug       Impact factor: 2.872

4.  Configuration and Performance of a Mobile (129)Xe Polarizer.

Authors:  Sergey E Korchak; Wolfgang Kilian; Lorenz Mitschang
Journal:  Appl Magn Reson       Date:  2012-11-10       Impact factor: 0.831

Review 5.  Functionalized 129Xe contrast agents for magnetic resonance imaging.

Authors:  Olena Taratula; Ivan J Dmochowski
Journal:  Curr Opin Chem Biol       Date:  2009-11-13       Impact factor: 8.822

Review 6.  Perspectives of hyperpolarized noble gas MRI beyond 3He.

Authors:  David M L Lilburn; Galina E Pavlovskaya; Thomas Meersmann
Journal:  J Magn Reson       Date:  2012-12-08       Impact factor: 2.229

7.  Distribution of hyperpolarized xenon in the brain following sensory stimulation: preliminary MRI findings.

Authors:  Mary L Mazzanti; Ronn P Walvick; Xin Zhou; Yanping Sun; Niral Shah; Joey Mansour; Jessica Gereige; Mitchell S Albert
Journal:  PLoS One       Date:  2011-07-15       Impact factor: 3.240

  7 in total

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