| Literature DB >> 10858261 |
R Banerjee1, J Anguita, E Fikrig.
Abstract
Mice deficient in phox (gp91(phox-/-)) or NOS2 (NOS2(-/-)) were infected with the agent of human granulocytic ehrlichiosis (HGE) to evaluate the importance of these pathways in the eradication of HGE bacteria. NOS2(-/-) mice had delayed clearance of the HGE agent in comparison to control or gp91(phox-/-) mice, suggesting that reactive nitrogen intermediates play a role in the early control of HGE.Entities:
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Year: 2000 PMID: 10858261 PMCID: PMC101771 DOI: 10.1128/IAI.68.7.4361-4362.2000
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441