Literature DB >> 1085449

Aplastic anemia: presence in human bone marrow of cells that suppress myelopoiesis.

W A Kagan, J A Ascensão, R N Pahwa, J A Hansen, G Goldstein, E B Valera, G S Incefy, M A Moore, R A Good.   

Abstract

Bone marrow from a patient with aplastic anemia was shown by multiple criteria to have a block in early myeloid differentiation. This block was overcome in vitro by elimination of marrow lymphocytes. Furthermore, this differentiation block was transferred in vitro to normal marrow by coculturing with the patient's marrow. We suggest that some cases of aplastic anemia may be due to an immunologically based suppression of marrow cell differentiation rather than to a defect in stem cells or their necessary inductive environment.

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Year:  1976        PMID： 1085449      PMCID： PMC430791          DOI： 10.1073/pnas.73.8.2890

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  A direct measurement of the radiation sensitivity of normal mouse bone marrow cells.

Authors:  J E TILL; E A McCULLOCH
Journal:  Radiat Res       Date:  1961-02       Impact factor: 2.841

2.  Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells.

Authors:  G Goldstein; M Scheid; U Hammerling; D H Schlesinger; H D Niall; E A Boyse
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Human lymphocyte-sheep erythrocyte rosette formation: some characteristics of the interaction.

Authors:  Z Bentwich; S D Douglas; F P Siegal; H G Kunkel
Journal:  Clin Immunol Immunopathol       Date:  1973-07

4.  The growth of mouse bone marrow cells in vitro.

Authors:  T R Bradley; D Metcalf
Journal:  Aust J Exp Biol Med Sci       Date:  1966-06

5.  Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.

Authors:  T A Waldmann; M Durm; S Broder; M Blackman; R M Blaese; W Strober
Journal:  Lancet       Date:  1974-09-14       Impact factor: 79.321

6.  Studies on red cell aplasia. 3. Treatment with horse antihuman thymocyte gamma globulin.

Authors:  S B Krantz
Journal:  Blood       Date:  1972-03       Impact factor: 22.113

7.  Prolonged remission of severe aplastic anemia after ALG pretreatment and HL-A-semi-incompatible bone-marrow cell transfusion.

Authors:  M Jeannet; A Rubinstein; B Pelet; H Kummer
Journal:  Transplant Proc       Date:  1974-12       Impact factor: 1.066

8.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

9.  Combined studies of complement receptor and surface immunoglobulin-bearing cells and sheep erythrocyte rosette-forming cells in normal and leukemic human lymphocytes.

Authors:  G D Ross; E M Rabellino; M J Polley; H M Grey
Journal:  J Clin Invest       Date:  1973-02       Impact factor: 14.808

10.  Aplastic anaemia: Evidence for an immunological mechanism.

Authors:  J Ascensão; R Pahwa; W Kagan; J Hansen; M Moore; R Good
Journal:  Lancet       Date:  1976-03-27       Impact factor: 79.321
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  34 in total

Review 1.  The diagnosis and treatment of aplastic anemia: a review.

Authors:  Maurizio Miano; Carlo Dufour
Journal:  Int J Hematol       Date:  2015-04-03       Impact factor: 2.490

Review 2.  Immune pathophysiology of aplastic anemia.

Authors:  Shinji Nakao; Xingmin Feng; Chiharu Sugimori
Journal:  Int J Hematol       Date:  2005-10       Impact factor: 2.490

3.  Hepatitis associated with aplastic anemia: do CD8(+) kupffer cells have a role in the pathogenesis?

Authors:  Cem Cengiz; Nesrin Turhan; O Faruk Yolcu; Sevinc Yilmaz
Journal:  Dig Dis Sci       Date:  2007-04-19       Impact factor: 3.199

4.  Clonal analysis of CD4+/CD8+ T cells in a patient with aplastic anemia.

Authors:  U Moebius; F Herrmann; T Hercend; S C Meuer
Journal:  J Clin Invest       Date:  1991-05       Impact factor: 14.808

5.  Pathology-important advances in clinical medicine: assessing fetal lung maturity.

Authors:  R K Wertz
Journal:  West J Med       Date:  1984-07

6.  Changes in cytokine profile pre- and post-immunosuppression in acquired aplastic anemia.

Authors:  Carlo Dufour; Elisa Ferretti; Francesca Bagnasco; Oriana Burlando; Marina Lanciotti; Ugo Ramenghi; Paola Saracco; Maria Teresa Van Lint; Daniela Longoni; Giovanni Fernando Torelli; Marta Pillon; Anna Locasciulli; Aldo Misuraca; Milena La Spina; Andrea Bacigalupo; Vito Pistoia; Anna Corcione; Johanna Svahn
Journal:  Haematologica       Date:  2009-07-07       Impact factor: 9.941

7.  Cytogenetic study is not essential in patients with aplastic anemia.

Authors:  Atreyee Dutta; Rajib De; Tuphan K Dolai; Pradip K Mitra; Ajanta Halder
Journal:  Am J Blood Res       Date:  2017-11-01

8.  Neutropenia in three patients with rheumatic disorders. Suppression of granulopoiesis by control-sensitive thymus-dependent lymphocytes.

Authors:  G C Bagby; J D Gabourel
Journal:  J Clin Invest       Date:  1979-07       Impact factor: 14.808

9.  Effect of T-lymphocytes on normal haemopoiesis: studies in congenitally athymic nude mice.

Authors:  G Harris; S N Wickramasinghe
Journal:  Blut       Date:  1979-09

Review 10.  Acquired aplastic anemia in children.

Authors:  Helge D Hartung; Timothy S Olson; Monica Bessler
Journal:  Pediatr Clin North Am       Date:  2013-10-16       Impact factor: 3.278
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