Literature DB >> 24237973

Acquired aplastic anemia in children.

Helge D Hartung1, Timothy S Olson, Monica Bessler.   

Abstract

This article provides a practice-based and concise review of the etiology, diagnosis, and management of acquired aplastic anemia in children. Bone marrow transplantation, immunosuppressive therapy, and supportive care are discussed in detail. The aim is to provide the clinician with a better understanding of the disease and to offer guidelines for the management of children with this uncommon yet serious disorder.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Acquired aplastic anemia; Bone marrow failure; Bone marrow transplant for severe aplastic anemia in children; Immune-mediated aplastic anemia; Immunosuppressive therapy for severe aplastic anemia in children

Mesh:

Substances:

Year:  2013        PMID: 24237973      PMCID: PMC3894991          DOI: 10.1016/j.pcl.2013.08.011

Source DB:  PubMed          Journal:  Pediatr Clin North Am        ISSN: 0031-3955            Impact factor:   3.278


  84 in total

1.  Functional characterization of CD4+ T cells in aplastic anemia.

Authors:  Shahram Kordasti; Judith Marsh; Sufyan Al-Khan; Jie Jiang; Alexander Smith; Azim Mohamedali; Pilar Perez Abellan; Caroline Veen; Benedetta Costantini; Austin G Kulasekararaj; Nana Benson-Quarm; Thomas Seidl; Syed A Mian; Farzin Farzaneh; Ghulam J Mufti
Journal:  Blood       Date:  2011-12-02       Impact factor: 22.113

2.  TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements.

Authors:  Hong-Yan Du; Elena Pumbo; Jennifer Ivanovich; Ping An; Richard T Maziarz; Ulrike M Reiss; Deborah Chirnomas; Akiko Shimamura; Adrianna Vlachos; Jeffrey M Lipton; Rakesh K Goyal; Frederick Goldman; David B Wilson; Philip J Mason; Monica Bessler
Journal:  Blood       Date:  2008-10-17       Impact factor: 22.113

3.  Fludarabine, cyclophosphamide and anti-thymocyte globulin for alternative donor transplants in acquired severe aplastic anemia: a report from the EBMT-SAA Working Party.

Authors:  A Bacigalupo; F Locatelli; E Lanino; J Marsh; G Socié; S Maury; A Prete; A Locasciulli; S Cesaro; J Passweg
Journal:  Bone Marrow Transplant       Date:  2005-12       Impact factor: 5.483

4.  The Third Consensus Conference on the treatment of aplastic anemia.

Authors:  Seiji Kojima; Shinji Nakao; Neal Young; Andrea Bacigalupo; Gerard Gerard; Naoto Hirano; Jaroslaw Maciejewski; Joachim Deeg; Judith Marsh; Feng-Kui Zhang; Jong Wook Lee; Keiya Ozawa
Journal:  Int J Hematol       Date:  2011-05-27       Impact factor: 2.490

5.  Roles of DRB1 *1501 and DRB1 *1502 in the pathogenesis of aplastic anemia.

Authors:  Chiharu Sugimori; Hirohito Yamazaki; Xingmin Feng; Kanako Mochizuki; Yukio Kondo; Akiyoshi Takami; Tatsuya Chuhjo; Akinori Kimura; Masanao Teramura; Hideaki Mizoguchi; Mitsuhiro Omine; Shinji Nakao
Journal:  Exp Hematol       Date:  2007-01       Impact factor: 3.084

6.  Granulocyte transfusions in severe aplastic anemia: an eleven-year experience.

Authors:  Karen Quillen; Edward Wong; Phillip Scheinberg; Neal S Young; Thomas J Walsh; Colin O Wu; Susan F Leitman
Journal:  Haematologica       Date:  2009-12       Impact factor: 9.941

7.  Retreatment with rabbit anti-thymocyte globulin and ciclosporin for patients with relapsed or refractory severe aplastic anaemia.

Authors:  Phillip Scheinberg; Olga Nunez; Neal S Young
Journal:  Br J Haematol       Date:  2006-06       Impact factor: 6.998

8.  Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine.

Authors:  Phillip Scheinberg; Colin O Wu; Olga Nunez; Neal S Young
Journal:  J Pediatr       Date:  2008-07-30       Impact factor: 4.406

9.  Diagnosing PNH with FLAER and multiparameter flow cytometry.

Authors:  D Robert Sutherland; Nancy Kuek; Jeff Davidson; David Barth; Hong Chang; Erik Yeo; Sylvia Bamford; Ian Chin-Yee; Michael Keeney
Journal:  Cytometry B Clin Cytom       Date:  2007-05       Impact factor: 3.058

10.  Bone marrow transplantation in pediatric patients with severe aplastic anemia: cyclophosphamide and anti-thymocyte globulin conditioning followed by recombinant human granulocyte-macrophage colony stimulating factor.

Authors:  N Bunin; A Leahey; N Kamani; C August
Journal:  J Pediatr Hematol Oncol       Date:  1996-02       Impact factor: 1.289

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  11 in total

1.  CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia.

Authors:  Christina Arieta Kuksin; Gabriela Gonzalez-Perez; Lisa M Minter
Journal:  Blood       Date:  2015-02-03       Impact factor: 22.113

2.  Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes.

Authors:  Caitlin Ritz; Wenzhao Meng; Natasha L Stanley; Miren L Baroja; Chong Xu; Patrick Yan; Alexander C Huang; Ryan Hausler; Peter Nicholas; Jian-Meng Fan; David Lieberman; Beatriz M Carreno; Eline T Luning Prak; Timothy S Olson; Daria V Babushok
Journal:  Blood Adv       Date:  2020-04-14

3.  Patient features and survival of pediatric aplastic anemia in the USA: a large institution experience.

Authors:  M J Hossain; S Xie
Journal:  J Public Health (Oxf)       Date:  2019-06-01       Impact factor: 2.341

4.  Correlation analysis of severe aplastic anemia immunosuppressive therapy and human leukocyte antigen alleles in pediatric patients.

Authors:  Ru-Ting Fu; Hong-Man Xue; Bi-Hong Zhang; Jian Wang; Shao-Fen Lin; Chun Chen
Journal:  Exp Ther Med       Date:  2015-10-15       Impact factor: 2.447

Review 5.  Updated Guidelines for the Treatment of Acquired Aplastic Anemia in Children.

Authors:  Nao Yoshida; Seiji Kojima
Journal:  Curr Oncol Rep       Date:  2018-06-30       Impact factor: 5.075

6.  Umbilical cord blood transplantation supplemented with the infusion of mesenchymal stem cell for an adolescent patient with severe aplastic anemia: a case report and review of literature.

Authors:  Chengxin Luan; Runzhe Chen; Baoan Chen; Jiahua Ding; Ming Ni
Journal:  Patient Prefer Adherence       Date:  2015-06-11       Impact factor: 2.711

Review 7.  Microbe-Induced Inflammatory Signals Triggering Acquired Bone Marrow Failure Syndromes.

Authors:  J Luis Espinoza; Ritesh Kotecha; Shinji Nakao
Journal:  Front Immunol       Date:  2017-02-24       Impact factor: 7.561

8.  Cyclosporine Monotherapy in Pediatric Patients With Non-severe Aplastic Anemia: A Retrospective Analysis.

Authors:  Hongmin Li; Lingling Fu; Bixi Yang; Hui Chen; Jie Ma; Runhui Wu
Journal:  Front Med (Lausanne)       Date:  2022-03-07

9.  Disrupted lymphocyte homeostasis in hepatitis-associated acquired aplastic anemia is associated with short telomeres.

Authors:  Daria V Babushok; Anne-Laure Grignon; Yimei Li; Jamie Atienza; Hongbo M Xie; Ho-Sun Lam; Helge Hartung; Monica Bessler; Timothy S Olson
Journal:  Am J Hematol       Date:  2016-02       Impact factor: 10.047

Review 10.  Evaluation and Management of Chronic Pancytopenia.

Authors:  Richa Sharma; Grzegorz Nalepa
Journal:  Pediatr Rev       Date:  2016-03
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