Literature DB >> 10853670

New fluorogenic substrate for the first continuous steroid sulfatase assay.

M Bilban1, A Billich, M Auer, P Nussbaumer.   

Abstract

The screening for new inhibitors of steroid sulfatase requires an efficient test system. To overcome the shortcomings of the available discontinuous fluorimetric assay, several coumarin-type compounds were investigated as potential new substrates. 3,4-Benzocoumarin 7-O-sulfate was found to have appropriate substrate properties for the establishment of the first direct continuous assay of steroid sulfatase.

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Year:  2000        PMID： 10853670     DOI： 10.1016/s0960-894x(00)00144-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

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Authors:  Elizabeth L Smith; Carolyn R Bertozzi; Kimberly E Beatty
Journal:  Chembiochem       Date:  2014-04-24       Impact factor: 3.164

Review 2.  A review of coumarin derivatives in pharmacotherapy of breast cancer.

Authors:  Musiliyu A Musa; John S Cooperwood; M Omar F Khan
Journal:  Curr Med Chem       Date:  2008       Impact factor: 4.530

3.  Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains.

Authors:  Kimberly E Beatty; Monique Williams; Brian L Carlson; Benjamin M Swarts; Robin M Warren; Paul D van Helden; Carolyn R Bertozzi
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-22       Impact factor: 11.205
  3 in total

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