Literature DB >> 10852438

Osteoporosis: an unusual presentation of childhood Crohn's disease.

M Thearle1, M Horlick, J P Bilezikian, J Levy, J M Gertner, L S Levine, M Harbison, W Berdon, S E Oberfield.   

Abstract

Osteoporosis is known to be associated with Crohn's disease. We report a 12-yr-old boy without a history of steroid use, in whom severe osteoporosis and multiple collapsed vertebrae were the presenting manifestations of Crohn's disease. After treatment of the Crohn's disease, he resumed normal growth and progressed through puberty. Concomitantly, he demonstrated a substantial recovery of vertebral bone mineral density and structure. Possible pathophysiological mechanisms underlying the osteoporosis and the subsequent improvement in bone density are discussed.

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Year:  2000        PMID： 10852438     DOI： 10.1210/jcem.85.6.6640

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  17 in total

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4.  Colitis, independent of macronutrient intake, compromises bone structure and strength in growing piglets.

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Review 7.  Perspectives on osteoporosis in pediatric inflammatory bowel disease.

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Journal:  Curr Gastroenterol Rep       Date:  2003-06

8.  Development of extraintestinal manifestations in pediatric patients with inflammatory bowel disease.

Authors:  Folashade Adebisi Jose; Elizabeth A Garnett; Eric Vittinghoff; George D Ferry; Harland S Winter; Robert N Baldassano; Barbara S Kirschner; Stanley A Cohen; Benjamin D Gold; Oren Abramson; Melvin B Heyman
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9.  Iliac bone histomorphometry in children with newly diagnosed inflammatory bowel disease.

Authors:  L M Ward; F Rauch; M A Matzinger; E I Benchimol; M Boland; D R Mack
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10.  Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report.

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Journal:  Exp Ther Med       Date:  2018-02-28       Impact factor: 2.447
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