Literature DB >> 12734045

Perspectives on osteoporosis in pediatric inflammatory bowel disease.

Manisha Harpavat1, David J Keljo.   

Abstract

Osteoporosis is now recognized as a problem in children with chronic illness. Decreased bone mineral density and increased risk of fracture have been reported in children with inflammatory bowel disease (IBD). Recent studies have led to a better understanding of the pathogenesis of bone loss. There are many risk factors for osteopenia and osteoporosis in children with IBD. Dual-energy x-ray absorptiometry remains the diagnostic procedure of choice for assessment of bone mineral density, but other modalities are being explored. Guidelines for diagnosis and treatment of osteoporosis in children have not been established. This article reviews the current understanding of osteopenia and osteoporosis in children with IBD.

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Year:  2003        PMID: 12734045     DOI: 10.1007/s11894-003-0024-8

Source DB:  PubMed          Journal:  Curr Gastroenterol Rep        ISSN: 1522-8037


  92 in total

1.  Bone density reduction in patients with Crohn disease and associations with demographic and disease variables: cross-sectional data from a population-based study.

Authors:  G Haugeberg; K Vetvik; A Stallemo; H Bitter; B Mikkelsen; M Stokkeland
Journal:  Scand J Gastroenterol       Date:  2001-07       Impact factor: 2.423

Review 2.  The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

Authors:  L C Hofbauer; S Khosla; C R Dunstan; D L Lacey; W J Boyle; B L Riggs
Journal:  J Bone Miner Res       Date:  2000-01       Impact factor: 6.741

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Journal:  Arch Dis Child       Date:  1997-04       Impact factor: 3.791

Review 4.  Inflammatory bowel disease and osteoporosis.

Authors:  H Andreassen; J Rungby; J F Dahlerup; L Mosekilde
Journal:  Scand J Gastroenterol       Date:  1997-12       Impact factor: 2.423

5.  Early changes in serum N-telopeptide and C-telopeptide cross-linked collagen type 1 predict long-term response to alendronate therapy in elderly women.

Authors:  S L Greenspan; H N Rosen; R A Parker
Journal:  J Clin Endocrinol Metab       Date:  2000-10       Impact factor: 5.958

6.  Bone mineral density and nutritional status in children with chronic inflammatory bowel disease.

Authors:  A M Boot; J Bouquet; E P Krenning; S M de Muinck Keizer-Schrama
Journal:  Gut       Date:  1998-02       Impact factor: 23.059

7.  Interleukin-6 inhibits bone formation in vitro.

Authors:  F J Hughes; G L Howells
Journal:  Bone Miner       Date:  1993-04

8.  Interpretation of bone mineral density values in pediatric Crohn's disease.

Authors:  D Herzog; N Bishop; F Glorieux; E G Seidman
Journal:  Inflamm Bowel Dis       Date:  1998-11       Impact factor: 5.325

9.  Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group.

Authors:  S R Cummings; D M Black; M C Nevitt; W Browner; J Cauley; K Ensrud; H K Genant; L Palermo; J Scott; T M Vogt
Journal:  Lancet       Date:  1993-01-09       Impact factor: 79.321

10.  Interleukin-1 beta stimulates bone resorption and inhibits bone formation in vivo.

Authors:  L Nguyen; F E Dewhirst; P V Hauschka; P Stashenko
Journal:  Lymphokine Cytokine Res       Date:  1991-04
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