Literature DB >> 10798684

Monte Carlo modeling of the transverse-axis dose distribution of the model 200 103Pd interstitial brachytherapy source.

J F Williamson1.   

Abstract

This study presents the first theoretical analysis of the absolute dose-rate distribution about the Model 200 103Pd interstitial brachytherapy source. Monte Carlo photon-transport (MCPT) simulation techniques have been used to evaluate the transverse-axis dose-rate distribution of the Model 200 source as a function of thickness of the Pd metal coating (containing the 103Pd) plated onto the surfaces of right cylindrical graphite pellets contained within the seed. The dose-rate constant, A, was realistically estimated by simulating the wide-angle, free-air chamber (WAFAC) calibration geometry. The WAFAC is the experimental realization of NIST's (National Institute of Standards and Technology) recently implemented primary standard of air-kerma strength (S(K)). Our results show that polar angle- and distance-dependent oblique filtration and shielding effects induce significant and unexpected photon fluence anisotropy near the transverse-axis and inverse square law deviations at typical calibration distances. Any source consisting of radioactivity deposited on a highly attenuating surface with sharp edges may exhibit such effects. In the case of the Model 200 seed, the Pd metal thickness does not significantly influence the relative dose distribution in water at distances less than 5 cm, but does make A sensitive to the S(K) measurement geometry. Fortunately, the WAFAC averages fluence over a sufficiently large aperture that the resultant A, 0.68 +/- 0.02 cGy x h(-1) x U(-1), is almost independent of Pd metal layer thickness and in close agreement with recent measurements and calculations. This value is 20% higher than that of the renormalized Task Group 43 A value.

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Year:  2000        PMID: 10798684     DOI: 10.1118/1.598924

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  8 in total

1.  A Monte Carlo evaluation for effects of probable dimensional uncertainties of low dose rate brachytherapy seeds on dose.

Authors:  Berkay Camgöz; Mehmet N Kumru
Journal:  Rep Pract Oncol Radiother       Date:  2014-07-19

2.  A directional 103Pd brachytherapy device: Dosimetric characterization and practical aspects for clinical use.

Authors:  Mark J Rivard
Journal:  Brachytherapy       Date:  2016-12-28       Impact factor: 2.362

3.  An EGSnrc investigation of the air-kerma strength, dose rate constant, and radial dose function of 125I brachytherapy sources.

Authors:  Sridhar Sahoo; T Palani Selvam
Journal:  Radiol Phys Technol       Date:  2009-07-11

4.  Fast patient-specific Monte Carlo brachytherapy dose calculations via the correlated sampling variance reduction technique.

Authors:  Andrew Sampson; Yi Le; Jeffrey F Williamson
Journal:  Med Phys       Date:  2012-02       Impact factor: 4.071

5.  New (125)I brachytherapy source IsoSeed I25.S17plus: Monte Carlo dosimetry simulation and comparison to sources of similar design.

Authors:  Evaggelos Pantelis; Panagiotis Papagiannis; Giorgos Anagnostopoulos; Dimos Baltas
Journal:  J Contemp Brachytherapy       Date:  2013-12-21

6.  New National Air-Kerma-Strength Standards for (125)I and (103)Pd Brachytherapy Seeds.

Authors:  Stephen M Seltzer; Paul J Lamperti; Robert Loevinger; Michael G Mitch; James T Weaver; Bert M Coursey
Journal:  J Res Natl Inst Stand Technol       Date:  2003-10-01

7.  Thermoluminescent and Monte Carlo dosimetry of IR06-103Pd brachytherapy source.

Authors:  Pooneh Saidi; Mahdi Sadeghi; S Hamed Hosseini; Claudio Tenreiro
Journal:  J Appl Clin Med Phys       Date:  2011-11-15       Impact factor: 2.102

8.  Monte Carlo dosimetric characterization of the IsoAid ADVANTAGE 103Pd brachytherapy source.

Authors:  Keith T Sowards
Journal:  J Appl Clin Med Phys       Date:  2007-03-20       Impact factor: 2.102

  8 in total

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