Literature DB >> 10790416

The coalescent with gene conversion.

C Wiuf1, J Hein.   

Abstract

In this article we develop a coalescent model with intralocus gene conversion. The distribution of the tract length is geometric in concordance with results published in the literature. We derive a simulation scheme and deduce a number of analytical results for this coalescent with gene conversion. We compare patterns of variability in samples simulated according to the coalescent with recombination with similar patterns simulated according to the coalescent with gene conversion alone. Further, an expression for the expected number of topology shifts in a sample of present-day sequences caused by gene conversion events is derived.

Mesh:

Year:  2000        PMID: 10790416      PMCID: PMC1461050     

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  12 in total

1.  Recombination as a point process along sequences.

Authors:  C Wiuf; J Hein
Journal:  Theor Popul Biol       Date:  1999-06       Impact factor: 1.570

2.  On the number of segregating sites in genetical models without recombination.

Authors:  G A Watterson
Journal:  Theor Popul Biol       Date:  1975-04       Impact factor: 1.570

Review 3.  The Holliday junction on its thirtieth anniversary.

Authors:  F W Stahl
Journal:  Genetics       Date:  1994-10       Impact factor: 4.562

4.  The repair of double-strand breaks in DNA; a model involving recombination.

Authors:  M A Resnick
Journal:  J Theor Biol       Date:  1976-06       Impact factor: 2.691

5.  Sampling theory for neutral alleles in a varying environment.

Authors:  R C Griffiths; S Tavaré
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1994-06-29       Impact factor: 6.237

6.  Properties of a neutral allele model with intragenic recombination.

Authors:  R R Hudson
Journal:  Theor Popul Biol       Date:  1983-04       Impact factor: 1.570

7.  Line-of-descent and genealogical processes, and their applications in population genetics models.

Authors:  S Tavaré
Journal:  Theor Popul Biol       Date:  1984-10       Impact factor: 1.570

8.  Meiotic roles of crossing-over and of gene conversion.

Authors:  A T Carpenter
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1984

9.  On the number of ancestors to a DNA sequence.

Authors:  C Wiuf; J Hein
Journal:  Genetics       Date:  1997-11       Impact factor: 4.562

10.  Meiotic gene conversion tract length distribution within the rosy locus of Drosophila melanogaster.

Authors:  A J Hilliker; G Harauz; A G Reaume; M Gray; S H Clark; A Chovnick
Journal:  Genetics       Date:  1994-08       Impact factor: 4.562

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  75 in total

1.  Evaluation of methods for detecting recombination from DNA sequences: computer simulations.

Authors:  D Posada; K A Crandall
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-20       Impact factor: 11.205

2.  Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels.

Authors:  L Frisse; R R Hudson; A Bartoszewicz; J D Wall; J Donfack; A Di Rienzo
Journal:  Am J Hum Genet       Date:  2001-08-29       Impact factor: 11.025

3.  Consequences of recombination on traditional phylogenetic analysis.

Authors:  M H Schierup; J Hein
Journal:  Genetics       Date:  2000-10       Impact factor: 4.562

4.  The coalescent and infinite-site model of a small multigene family.

Authors:  Hideki Innan
Journal:  Genetics       Date:  2003-02       Impact factor: 4.562

5.  Estimating the contribution of mutation, recombination and gene conversion in the generation of haplotypic diversity.

Authors:  Peter L Morrell; Donna M Toleno; Karen E Lundy; Michael T Clegg
Journal:  Genetics       Date:  2006-04-19       Impact factor: 4.562

6.  A coalescent model of recombination hotspots.

Authors:  Carsten Wiuf; David Posada
Journal:  Genetics       Date:  2003-05       Impact factor: 4.562

7.  Genome-level evolution of resistance genes in Arabidopsis thaliana.

Authors:  Andrew Baumgarten; Steven Cannon; Russ Spangler; Georgiana May
Journal:  Genetics       Date:  2003-09       Impact factor: 4.562

8.  Insights into recombination from patterns of linkage disequilibrium in humans.

Authors:  Susan E Ptak; Kristian Voelpel; Molly Przeworski
Journal:  Genetics       Date:  2004-05       Impact factor: 4.562

9.  Estimating the rate of gene conversion on human chromosome 21.

Authors:  Badri Padhukasahasram; Paul Marjoram; Magnus Nordborg
Journal:  Am J Hum Genet       Date:  2004-07-12       Impact factor: 11.025

10.  Estimating recombination rates using three-site likelihoods.

Authors:  Jeffrey D Wall
Journal:  Genetics       Date:  2004-07       Impact factor: 4.562

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