Literature DB >> 12618415

The coalescent and infinite-site model of a small multigene family.

Hideki Innan1.   

Abstract

The infinite-site model of a small multigene family with two duplicated genes is studied. The expectations of the amounts of nucleotide variation within and between two genes and linkage disequilibrium are obtained, and a coalescent-based method for simulating patterns of polymorphism in a small multigene family is developed. The pattern of DNA variation is much more complicated than that in a single-copy gene, which can be simulated by the standard coalescent. Using the coalescent simulation of duplicated genes, the applicability of statistical tests of neutrality to multigene families is considered.

Mesh：

Year:  2003        PMID： 12618415      PMCID： PMC1462437     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  18 in total

1.  The coalescent with gene conversion.

Authors:  C Wiuf; J Hein
Journal:  Genetics       Date:  2000-05       Impact factor: 4.562

2.  Recent segmental duplications in the human genome.

Authors:  Jeffrey A Bailey; Zhiping Gu; Royden A Clark; Knut Reinert; Rhea V Samonte; Stuart Schwartz; Mark D Adams; Eugene W Myers; Peter W Li; Evan E Eichler
Journal:  Science       Date:  2002-08-09       Impact factor: 47.728

3.  Segregating sites in a gene conversion model with mutation.

Authors:  M Bahlo
Journal:  Theor Popul Biol       Date:  1998-12       Impact factor: 1.570

4.  Molecular evolution of duplicated amylase gene regions in Drosophila melanogaster: evidence of positive selection in the coding regions and selective constraints in the cis-regulatory regions.

Authors:  H Araki; N Inomata; T Yamazaki
Journal:  Genetics       Date:  2001-02       Impact factor: 4.562

5.  The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations.

Authors:  M Kimura
Journal:  Genetics       Date:  1969-04       Impact factor: 4.562

6.  Properties of a neutral allele model with intragenic recombination.

Authors:  R R Hudson
Journal:  Theor Popul Biol       Date:  1983-04       Impact factor: 1.570

7.  On the evolution of multigene families.

Authors:  T Ohta
Journal:  Theor Popul Biol       Date:  1983-04       Impact factor: 1.570

8.  The evolution of multigene families under intrachromosomal gene conversion.

Authors:  T Nagylaki
Journal:  Genetics       Date:  1984-03       Impact factor: 4.562

9.  Allelic and nonallelic homology of a supergene family.

Authors:  T Ohta
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

10.  Rapid concerted evolution via gene conversion at the Drosophila hsp70 genes.

Authors:  Brian R Bettencourt; Martin E Feder
Journal:  J Mol Evol       Date:  2002-05       Impact factor: 2.395
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  40 in total

1.  A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.

Authors:  Hideki Innan
Journal:  Proc Natl Acad Sci U S A       Date:  2003-07-11       Impact factor: 11.205

2.  The effect of gene conversion on the divergence between duplicated genes.

Authors:  Kosuke M Teshima; Hideki Innan
Journal:  Genetics       Date:  2004-03       Impact factor: 4.562

3.  The coalescent with selection on copy number variants.

Authors:  Kosuke M Teshima; Hideki Innan
Journal:  Genetics       Date:  2011-12-14       Impact factor: 4.562

4.  Unified modeling of gene duplication, loss, and coalescence using a locus tree.

Authors:  Matthew D Rasmussen; Manolis Kellis
Journal:  Genome Res       Date:  2012-01-23       Impact factor: 9.043

5.  Diversity-enhancing selection acts on a female reproductive protease family in four subspecies of Drosophila mojavensis.

Authors:  Erin S Kelleher; Nathaniel L Clark; Therese A Markow
Journal:  Genetics       Date:  2011-01-06       Impact factor: 4.562

6.  Modified Hudson-Kreitman-Aguade test and two-dimensional evaluation of neutrality tests.

Authors:  Hideki Innan
Journal:  Genetics       Date:  2006-04-19       Impact factor: 4.562

7.  On the genealogy of a duplicated microsatellite.

Authors:  Kangyu Zhang; Noah A Rosenberg
Journal:  Genetics       Date:  2007-10-18       Impact factor: 4.562

8.  Buffering of crucial functions by paleologous duplicated genes may contribute cyclicality to angiosperm genome duplication.

Authors:  Brad A Chapman; John E Bowers; Frank A Feltus; Andrew H Paterson
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-08       Impact factor: 11.205

9.  Signatures of selection and gene conversion associated with human color vision variation.

Authors:  Brian C Verrelli; Sarah A Tishkoff
Journal:  Am J Hum Genet       Date:  2004-07-13       Impact factor: 11.025

10.  Evidence that strong positive selection drives neofunctionalization in the tandemly duplicated polyhomeotic genes in Drosophila.

Authors:  Steffen Beisswanger; Wolfgang Stephan
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-01       Impact factor: 11.205
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