| Literature DB >> 10770784 |
J C Fung-Tomc1, E Gradelski, L Valera, B Kolek, D P Bonner.
Abstract
Killing rates of fluoroquinolones, beta-lactams, and vancomycin were compared against Enterobacteriaceae, Staphylococcus aureus, pneumococci, streptococci, and Enterococcus faecalis. The times required for fluoroquinolones to decrease viability by 3 log(10) were 1.5 h for Enterobacteriaceae, 4 to 6 h for staphylococci, and >/=6 h for streptococci and enterococci. Thus, the rate of killing by fluoroquinolones is organism group dependent; overall, they killed more rapidly than beta-lactams and vancomycin.Entities:
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Year: 2000 PMID: 10770784 PMCID: PMC89877 DOI: 10.1128/AAC.44.5.1377-1380.2000
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191