Literature DB >> 10770784

Comparative killing rates of fluoroquinolones and cell wall-active agents.

J C Fung-Tomc1, E Gradelski, L Valera, B Kolek, D P Bonner.   

Abstract

Killing rates of fluoroquinolones, beta-lactams, and vancomycin were compared against Enterobacteriaceae, Staphylococcus aureus, pneumococci, streptococci, and Enterococcus faecalis. The times required for fluoroquinolones to decrease viability by 3 log(10) were 1.5 h for Enterobacteriaceae, 4 to 6 h for staphylococci, and >/=6 h for streptococci and enterococci. Thus, the rate of killing by fluoroquinolones is organism group dependent; overall, they killed more rapidly than beta-lactams and vancomycin.

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Year:  2000        PMID: 10770784      PMCID: PMC89877          DOI: 10.1128/AAC.44.5.1377-1380.2000

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  12 in total

1.  Bactericidal index: a new way to assess quinolone bactericidal activity in vitro.

Authors:  I Morrissey
Journal:  J Antimicrob Chemother       Date:  1997-06       Impact factor: 5.790

2.  Efficacy of trovafloxacin in treatment of experimental staphylococcal or streptococcal endocarditis.

Authors:  J M Entenza; J Vouillamoz; M P Glauser; P Moreillon
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

3.  The fluoroquinolones exert a reduced rate of kill against Enterococcus faecalis.

Authors:  C S Lewin; I Morrissey; J T Smith
Journal:  J Pharm Pharmacol       Date:  1991-07       Impact factor: 3.765

4.  Anti-pneumococcal activity of gatifloxacin compared with other quinolone and non-quinolone agents.

Authors:  D B Hoellman; G Lin; M R Jacobs; P C Appelbaum
Journal:  J Antimicrob Chemother       Date:  1999-05       Impact factor: 5.790

5.  In vitro activity of the combination of trovafloxacin and other antibiotics against enterococci.

Authors:  D G Schick; H N Canawati; J Z Montgomerie
Journal:  Diagn Microbiol Infect Dis       Date:  1997-12       Impact factor: 2.803

6.  Bactericidal activity of trovafloxacin (CP-99,219).

Authors:  I Morrissey
Journal:  J Antimicrob Chemother       Date:  1996-12       Impact factor: 5.790

7.  Efficacy of temafloxacin in experimental Streptococcus adjacens endocarditis and autoradiographic diffusion pattern of [14C]temafloxacin in cardiac vegetations.

Authors:  A C Cremieux; A Saleh-Mghir; J M Vallois; B Maziere; M Muffat-Joly; C Devine; A Bouvet; J J Pocidalo; C Carbon
Journal:  Antimicrob Agents Chemother       Date:  1992-10       Impact factor: 5.191

8.  Parenteral sparfloxacin compared with ceftriaxone in treatment of experimental endocarditis due to penicillin-susceptible and -resistant streptococci.

Authors:  J M Entenza; M Blatter; M P Glauser; P Moreillon
Journal:  Antimicrob Agents Chemother       Date:  1994-12       Impact factor: 5.191

9.  In vitro activity of pefloxacin against gram-negative and gram-positive bacteria in comparison with other antibiotics.

Authors:  E Debbia; G C Schito; G Nicoletti; A Speciale
Journal:  Chemioterapia       Date:  1987-10

10.  Antibacterial activity of a 1,8-naphthyridine quinolone, PD 131628.

Authors:  C S Lewin
Journal:  J Med Microbiol       Date:  1992-05       Impact factor: 2.472

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  10 in total

1.  Pharmacodynamic functions: a multiparameter approach to the design of antibiotic treatment regimens.

Authors:  Roland R Regoes; Camilla Wiuff; Renata M Zappala; Kim N Garner; Fernando Baquero; Bruce R Levin
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

2.  The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins.

Authors:  Hsun-Cheng Su; Kevin Ramkissoon; Janet Doolittle; Martha Clark; Jainab Khatun; Ashley Secrest; Matthew C Wolfgang; Morgan C Giddings
Journal:  Antimicrob Agents Chemother       Date:  2010-08-09       Impact factor: 5.191

3.  Probing the Mechanism of LAL-32, a Gold Nanoparticle-Based Antibiotic Discovered through Small Molecule Variable Ligand Display.

Authors:  Rose Byrne-Nash; Danielle M Lucero; Niki A Osbaugh; Roberta J Melander; Christian Melander; Daniel L Feldheim
Journal:  Bioconjug Chem       Date:  2017-06-27       Impact factor: 4.774

4.  Mechanism-based pharmacodynamic models of fluoroquinolone resistance in Staphylococcus aureus.

Authors:  Philip Chung; Patrick J McNamara; Jeffrey J Campion; Martin E Evans
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

5.  Phenotypic tolerance: antibiotic enrichment of noninherited resistance in bacterial populations.

Authors:  C Wiuff; R M Zappala; R R Regoes; K N Garner; F Baquero; B R Levin
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

6.  Translating slow-binding inhibition kinetics into cellular and in vivo effects.

Authors:  Grant K Walkup; Zhiping You; Philip L Ross; Eleanor K H Allen; Fereidoon Daryaee; Michael R Hale; John O'Donnell; David E Ehmann; Virna J A Schuck; Ed T Buurman; Allison L Choy; Laurel Hajec; Kerry Murphy-Benenato; Valerie Marone; Sara A Patey; Lena A Grosser; Michele Johnstone; Stephen G Walker; Peter J Tonge; Stewart L Fisher
Journal:  Nat Chem Biol       Date:  2015-04-20       Impact factor: 15.040

7.  Synergistic activities of gatifloxacin in combination with other antimicrobial agents against Pseudomonas aeruginosa and related species.

Authors:  E Gradelski; L Valera; D Bonner; J Fung-Tomc
Journal:  Antimicrob Agents Chemother       Date:  2001-11       Impact factor: 5.191

8.  Modeling the growth dynamics of multiple Escherichia coli strains in the pig intestine following intramuscular ampicillin treatment.

Authors:  Amais Ahmad; Camilla Zachariasen; Lasse Engbo Christiansen; Kaare Græsbøll; Nils Toft; Louise Matthews; Søren Saxmose Nielsen; John Elmerdahl Olsen
Journal:  BMC Microbiol       Date:  2016-09-06       Impact factor: 3.605

9.  Population Density Modulates Drug Inhibition and Gives Rise to Potential Bistability of Treatment Outcomes for Bacterial Infections.

Authors:  Jason Karslake; Jeff Maltas; Peter Brumm; Kevin B Wood
Journal:  PLoS Comput Biol       Date:  2016-10-20       Impact factor: 4.475

10.  Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli.

Authors:  Amais Ahmad; Camilla Zachariasen; Lasse Engbo Christiansen; Kaare Græsbøll; Nils Toft; Louise Matthews; Peter Damborg; Yvonne Agersø; John Elmerdahl Olsen; Søren Saxmose Nielsen
Journal:  Acta Vet Scand       Date:  2015-11-24       Impact factor: 1.695

  10 in total

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