Literature DB >> 10727370

Treatment of ruptured abdominal aortic aneurysm, a permanent challenge or a waste of resources? Prediction of outcome using a multi-organ-dysfunction score.

H W Kniemeyer1, T Kessler, P U Reber, H B Ris, H Hakki, M K Widmer.   

Abstract

OBJECTIVES: in a retrospective study, attempts have been made to identify individual organ-dysfunction risk profiles influencing the outcome after surgery for ruptured abdominal aortic aneurysms.
METHODS: out of 235 patients undergoing graft replacement for abdominal aortic aneurysms, 57 (53 men, four women, mean age 72 years [s.d. 8.8]) were treated for ruptured aneurysms in a 3-year period. Forty-eight preoperative, 13 intraoperative and 34 postoperative variables were evaluated statistically. A simple multi-organ dysfunction (MOD) score was adopted.
RESULTS: the perioperative mortality was 32%. Three patients died intraoperatively, four within 48 h and 11 died later. A significant influence for pre-existing risk factors was identified only for cardiovascular diseases. Multiple linear-regression analysis indicated that a haemoglobin <90 g/l, systolic blood pressure <80 mmHg and ECG signs of ischaemia at admission were highly significant risk factors. The cause of death for patients, who died more than 48 h postoperatively, was mainly MOD. All patients with a MOD score >/=4 died (n=7). These patients required 27% of the intensive-care unit (ICU) days of all patients and 72% of the ICU days of the non-survivors.
CONCLUSION: patients with ruptured aortic aneurysms from treatment should not be excluded. However, a physiological scoring system after 48 h appears justifiable in order to decide on the appropriateness of continual ICU support. Copyright 2000 Harcourt Publishers Ltd.

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Mesh:

Year:  2000        PMID: 10727370     DOI: 10.1053/ejvs.1999.0980

Source DB:  PubMed          Journal:  Eur J Vasc Endovasc Surg        ISSN: 1078-5884            Impact factor:   7.069


  32 in total

1.  Risk as feelings in the effect of patient outcomes on physicians' future treatment decisions: a randomized trial and manipulation validation.

Authors:  Joshua A Hemmerich; Arthur S Elstein; Margaret L Schwarze; Elizabeth Ghini Moliski; William Dale
Journal:  Soc Sci Med       Date:  2012-04-20       Impact factor: 4.634

2.  Endovascular grafts and other image-guided catheter-based adjuncts to improve the treatment of ruptured aortoiliac aneurysms.

Authors:  T Ohki; F J Veith
Journal:  Ann Surg       Date:  2000-10       Impact factor: 12.969

3.  In Vivo Molecular Characterization of Abdominal Aortic Aneurysms Using Fibrin-Specific Magnetic Resonance Imaging.

Authors:  René M Botnar; Julia Brangsch; Carolin Reimann; Christian H P Janssen; Reza Razavi; Bernd Hamm; Marcus R Makowski
Journal:  J Am Heart Assoc       Date:  2018-05-30       Impact factor: 5.501

4.  Predictors of mortality after emergency or elective repair of abdominal aortic aneurysm in a Japanese population.

Authors:  Atsuko Nakayama; Hiroyuki Morita; Tetsuro Miyata; Katsuyuki Hoshina; Masatoshi Nagayama; Shuichiro Takanashi; Tetsuya Sumiyoshi; Issei Komuro; Ryozo Nagai
Journal:  Heart Vessels       Date:  2012-12-30       Impact factor: 2.037

5.  Histopathological analysis of cellular localization of cathepsins in abdominal aortic aneurysm wall.

Authors:  Fabian Lohoefer; Christian Reeps; Christina Lipp; Martina Rudelius; Alexander Zimmermann; Stefan Ockert; Hans-Henning Eckstein; Jaroslav Pelisek
Journal:  Int J Exp Pathol       Date:  2012-08       Impact factor: 1.925

6.  Patient-Specific Prediction of Abdominal Aortic Aneurysm Expansion Using Bayesian Calibration.

Authors:  Liangliang Zhang; Zhenxiang Jiang; Jongeun Choi; Chae Young Lim; Tapabrata Maiti; Seungik Baek
Journal:  IEEE J Biomed Health Inform       Date:  2019-01-30       Impact factor: 5.772

7.  Prognostic factors associated with mortality in patients undergoing emergency surgery for abdominal aortic aneurysms.

Authors:  Yukari Koga; Yasunori Mishima; Masato Hara; Teruyuki Hiraki; Kazuo Ushijima
Journal:  J Anesth       Date:  2011-06-24       Impact factor: 2.078

8.  Investigation of reference levels and radiation dose associated with abdominal EVAR (endovascular aneurysm repair) procedures across several European Centres.

Authors:  E Tuthill; L O'Hora; M O'Donohoe; S Panci; P Gilligan; D Campion; R Trenti; E Fox; D Catania; L Rainford
Journal:  Eur Radiol       Date:  2017-05-18       Impact factor: 5.315

9.  Endovascular treatment of ruptured abdominal aortic aneurysms: aorto-uni-iliac or bifurcated endograft?

Authors:  G Carrafiello; G Piffaretti; D Laganà; F Fontana; M Mangini; A M Ierardi; F Piacentino; A Canì; G Mariscalco; A Di Massa; S Cuffari; P Castelli; C Fugazzola
Journal:  Radiol Med       Date:  2011-09-02       Impact factor: 3.469

10.  IL-1β (Interleukin-1β) and TNF-α (Tumor Necrosis Factor-α) Impact Abdominal Aortic Aneurysm Formation by Differential Effects on Macrophage Polarization.

Authors:  Rishi Batra; Melissa K Suh; Jeffrey S Carson; Matthew A Dale; Trevor M Meisinger; Matthew Fitzgerald; Patrick J Opperman; Jiangtao Luo; Iraklis I Pipinos; Wanfen Xiong; B Timothy Baxter
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-12-07       Impact factor: 8.311

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