Literature DB >> 21701923

Prognostic factors associated with mortality in patients undergoing emergency surgery for abdominal aortic aneurysms.

Yukari Koga1, Yasunori Mishima, Masato Hara, Teruyuki Hiraki, Kazuo Ushijima.   

Abstract

PURPOSE: Surgical mortality rates following emergency surgery for ruptured abdominal aortic aneurysms (AAAs) remain high. This study investigated the mortality rate and identified prognostic factors affecting mortality in patients undergoing emergency repair of AAAs in our hospital.
METHODS: Between January 2005 and June 2010, a total of 42 patients underwent emergency surgery for AAAs and were included in this retrospective study. The following variables concerning each patient were collected by chart review and compared between survivors and nonsurvivors: age; gender; preoperative levels of hemoglobin (Hb), hematocrit (Ht), platelets (Plts), base excess (BE), and serum glucose and lactate; presence of preoperative shock defined as hypotension (systolic blood pressure of less than 80 mmHg); incidence of blood transfusion, whether AAA was ruptured or impending; interval from admission to the hospital or arrival in the operating room until aortic cross-clamping; surgical duration; and volume of intraoperative blood loss and transfusion, total fluid infusion, and urine output.
RESULTS: Nine patients died within 30 days postoperatively, a 30-day mortality rate of 21.4%. Among these nine nonsurvivors, eight had shown persistent preoperative shock (P = 0.0004 vs. survivors). Compared with the survivors, nonsurvivors were significantly older (P = 0.0052) and had lower preoperative levels of Hb/Ht (P < 0.0001), Plts (P = 0.0003), and BE (P < 0.0001), an elevated lactate level (P = 0.0048), shorter interval from admission (P = 0.0459) or arrival in the operating room (P = 0.0288) until aortic clamping, and intraoperatively more hemorrhage (P = 0.0038) associated with larger amounts of blood transfusion (P = 0.0083) and less urine output (P = 0.0004).
CONCLUSIONS: The authors clarified that certain features such as age, persistent preoperative shock, and greater amounts of transfusion associated with greater blood loss and anemia were factors affecting the mortality in patients undergoing emergency surgery for AAAs. It might be of great importance to correct preoperative shock and anemia caused by massive bleeding before the onset of hemodynamic deterioration.

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Year:  2011        PMID: 21701923     DOI: 10.1007/s00540-011-1185-5

Source DB:  PubMed          Journal:  J Anesth        ISSN: 0913-8668            Impact factor:   2.078


  31 in total

Review 1.  Abdominal compartment syndrome in vascular surgery - A review.

Authors:  G Ganeshanantham; S R Walsh; K Varty
Journal:  Int J Surg       Date:  2010-01-13       Impact factor: 6.071

2.  Preoperative haemodynamic parameters and the immediate outcome after open repair of ruptured abdominal aortic aneurysms.

Authors:  Salvatore Giordano; Fausto Biancari; Pertti Loponen; Jan-Ola Wistbacka; Michael Luther
Journal:  Interact Cardiovasc Thorac Surg       Date:  2009-06-30

3.  Ruptured abdominal aortic aneurysms: analysis of factors influencing surgical results in 184 patients.

Authors:  S Sasaki; M Sakuma; M Samejima; T Kunihara; N Shiiya; T Murashita; Y Matsui; K Yasuda
Journal:  J Cardiovasc Surg (Torino)       Date:  1999-06       Impact factor: 1.888

4.  Risk assessment in patients with ruptured abdominal aortic aneurysms.

Authors:  H W Kniemeyer; P U Reber; T Kessler; H Beckmann; H Hakki
Journal:  Acta Chir Belg       Date:  2002-06       Impact factor: 1.090

Review 5.  In patients with ruptured abdominal aortic aneurysm does endovascular repair improve 30-day mortality?

Authors:  Jake Foster; Jonathan Ghosh; Mohamed Baguneid
Journal:  Interact Cardiovasc Thorac Surg       Date:  2010-01-21

Review 6.  A meta-analysis of 21,178 patients undergoing open or endovascular repair of abdominal aortic aneurysm.

Authors:  R E Lovegrove; M Javid; T R Magee; R B Galland
Journal:  Br J Surg       Date:  2008-06       Impact factor: 6.939

7.  The effects of abdominal compartment hypertension after open and endovascular repair of a ruptured abdominal aortic aneurysm.

Authors:  Ragai R Makar; Stephen A Badger; Mark E O'Donnell; William Loan; Louis L Lau; Chee V Soong
Journal:  J Vasc Surg       Date:  2009-04       Impact factor: 4.268

8.  Long term relative survival after surgery for abdominal aortic aneurysm in western Australia: population based study.

Authors:  P E Norman; J B Semmens; M M Lawrence-Brown; C D Holman
Journal:  BMJ       Date:  1998-09-26

9.  Effect of the duration of symptoms, transport time, and length of emergency room stay on morbidity and mortality in patients with ruptured abdominal aortic aneurysms.

Authors:  M M Farooq; J A Freischlag; G R Seabrook; M R Moon; C Aprahamian; J B Towne
Journal:  Surgery       Date:  1996-01       Impact factor: 3.982

10.  Ruptured abdominal aortic aneurysms: factors affecting mortality rates.

Authors:  L M Harris; G L Faggioli; R Fiedler; G R Curl; J J Ricotta
Journal:  J Vasc Surg       Date:  1991-12       Impact factor: 4.268

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