Literature DB >> 10718388

Virtual endoscopy--comparison with colonoscopy in the detection of space-occupying lesions of the colon.

C L Kay1, D Kulling, R H Hawes, J W Young, P B Cotton.   

Abstract

BACKGROUND AND STUDY AIMS: A new technique has been described which combines abdominal helical computed tomography (CT) scanning and virtual reality computer technology, known as virtual colonoscopy (VC); the reconstructed images provide a simulation of the interior of the colon as viewed by endoscopy. We compared VC with conventional colonoscopy in patients with suspected or known colonic neoplasia. PATIENTS AND METHODS: A total of 38 patients, in whom there was a high likelihood of colonic polyps or cancer, underwent a noncontrast helical CT scan of the abdomen and pelvis after regular colonoscopy bowel preparation. The images were reconstructed into a VC presentation and compared with the subsequent conventional colonoscopy in a blinded manner.
RESULTS: Conventional colonoscopy identified a total of 24 polyps 5 mm or greater. VC correctly identified five of 13 polyps 5-9 mm in size, and ten of 11 lesions greater than or equal to 10 mm in diameter. The reasons for four missed lesions were identified as being secondary to a collapsed rectum in two patients and stool in the right colon in two patients. The sensitivity and specificity per patient of VC for lesions greater than or equal to 5 mm were 66.7% and 75.0% respectively, and for lesions greater than 1 cm were 90.0% and 82.1%, respectively.
CONCLUSIONS: Virtual colonoscopy is feasible, well tolerated, and capable of detecting most lesions greater than 10 mm in diameter. This technique is continuing to be developed and warrants further evaluation as a diagnostic and screening tool in colorectal neoplasia.

Entities:  

Mesh:

Year:  2000        PMID: 10718388     DOI: 10.1055/s-2000-100

Source DB:  PubMed          Journal:  Endoscopy        ISSN: 0013-726X            Impact factor:   10.093


  11 in total

Review 1.  Virtual endoscopy: current perspectives.

Authors:  Hajime Kuwayama; Mamoru Iimuro; Yoshinori Kitazumi; Gordon Luk
Journal:  J Gastroenterol       Date:  2002       Impact factor: 7.527

2.  Screening for colon cancer.

Authors:  J P Heiken
Journal:  Cancer Imaging       Date:  2006-10-31       Impact factor: 3.909

3.  Depth-map-based scene analysis for active navigation in virtual angioscopy.

Authors:  P Haigron; M E Bellemare; O Acosta; C Göksu; C Kulik; K Rioual; A Lucas
Journal:  IEEE Trans Med Imaging       Date:  2004-11       Impact factor: 10.048

4.  Computed tomographic colonography: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2003-10-01

Review 5.  Computed tomographic colonography: hope or hype?

Authors:  Otto Schiueh-Tzang Lin
Journal:  World J Gastroenterol       Date:  2010-02-28       Impact factor: 5.742

6.  Evaluation of contrast-enhanced computed tomographic colonography in detection of local recurrent colorectal cancer.

Authors:  Yau-Tong You; Chung-Rong Chang Chien; Jeng-Yi Wang; Koon-Kwan Ng; Jinn-Shiun Chen; Reiping Tang; Jy-Ming Chiang; Chien-Yuh Yeh; Pao-Shiu Hsieh
Journal:  World J Gastroenterol       Date:  2006-01-07       Impact factor: 5.742

7.  Validation of virtual colonoscopy in the detection of colorectal polyps and masses: rationale for proper study design.

Authors:  B C Pineau; E D Paskett; G J Chen; V L Durkalski; M A Espeland; D J Vining
Journal:  Int J Gastrointest Cancer       Date:  2001

8.  Performance of multidetector computed tomography colonography compared with conventional colonoscopy.

Authors:  Th Gluecker; G Dorta; W Keller; P Jornod; R Meuli; P Schnyder
Journal:  Gut       Date:  2002-08       Impact factor: 23.059

Review 9.  Virtual colonoscopy for colorectal cancer screening: current status.

Authors:  Jay P Heiken; Christine M Peterson; Christine O Menias
Journal:  Cancer Imaging       Date:  2005-11-23       Impact factor: 3.909

Review 10.  Hereditary colorectal cancer: screening and management.

Authors:  Angel Ferrández; James A DiSario
Journal:  Curr Treat Options Oncol       Date:  2002-12
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