Rationale for once-daily therapy in asthma: compliance issues.

Compliance in asthma is known to be poor. Once-daily treatment provides an additional therapeutic option for the clinician whose treatment aims include maximising treatment satisfaction and compliance. Once-daily treatment is preferred by some but not all patients and may lead to greater compliance in patients who are concerned about the effect of corticosteroids on their health. When switching to once-daily treatment, patients should be given a choice as to the time of treatment to minimise the impact of forgetting a dose.