Literature DB >> 1071015

Acute nonlymphocytic leukemia associated with nitrosourea chemotherapy: report of two cases.

R J Cohen, P H Wiernik, M D Walker.   

Abstract

Acute nonlymphocytic leukemia developed in two patients who were treated postoperatively with cytotoxic chemotherapy. Both patients survived more than 4 years after the diagnosis of brain tumor, and both had extended periods of myelosuppression secondary to nitrosourea chemotherapy. Nitrosourea therapy may have facilitated the development of acute leukemia in these patients.

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Year:  1976        PMID: 1071015

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


  10 in total

1.  Acute leukemia in a patient cured of diffuse histiocytic lymphoma.

Authors:  J P Dutcher; P H Wiernik
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

Review 2.  Treatments for astrocytic tumors in children: current and emerging strategies.

Authors:  Stanislaw R Burzynski
Journal:  Paediatr Drugs       Date:  2006       Impact factor: 3.022

3.  Methyl CCNU therapy linked leukemia.

Authors:  M R Shetty
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

Review 4.  Therapy-related myelodysplastic syndrome (t-MDS) in a patient with anaplastic astrocytoma: successful treatment with allogeneic bone marrow transplant.

Authors:  L R Rogers; N Janakiraman; C Kasten-Sportes; M L Rosenblum
Journal:  J Neurooncol       Date:  2001-05       Impact factor: 4.130

5.  Development of second malignancies in rats after cure of acute leukemia L 5222 by single doses of 2-chloroethylnitrosoureas.

Authors:  W J Zeller; D Schmähl
Journal:  J Cancer Res Clin Oncol       Date:  1979-09       Impact factor: 4.553

Review 6.  Carcinogenic N-nitroso compounds and their environmental significance.

Authors:  R Preussmann
Journal:  Naturwissenschaften       Date:  1984-01

7.  Cytogenetic studies in an acute leukemia patient following cerebellar astrocytoma.

Authors:  A Nora; R Heideman; D Peakman; H Morse
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

Review 8.  Acute leukemia following treatment of malignant glioma.

Authors:  J R Perry; M T Brown; J P Gockerman
Journal:  J Neurooncol       Date:  1998-10       Impact factor: 4.130

9.  Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas.

Authors:  Daniela A Bota; Annick Desjardins; Jennifer A Quinn; Mary L Affronti; Henry S Friedman
Journal:  Ther Clin Risk Manag       Date:  2007-10       Impact factor: 2.423

10.  Repair of O6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas.

Authors:  W J Bodell; T Aida; M S Berger; M L Rosenblum
Journal:  Environ Health Perspect       Date:  1985-10       Impact factor: 9.031

  10 in total

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