Literature DB >> 227910

Development of second malignancies in rats after cure of acute leukemia L 5222 by single doses of 2-chloroethylnitrosoureas.

W J Zeller, D Schmähl.   

Abstract

After cure of rat leukemia L 5222 in 79 BD IX rats by single doses of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) or 1-(2-hydroxyethyl)-3-(2-chloroethyl)-3-nitrosourea (Hydroxyethyl-CNU) a total of 9 rats (11%) developed secondary malignomas.

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Year:  1979        PMID： 227910     DOI： 10.1007/bf00411113

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  5 in total

1.  Acute leukemia complicating treatment of glioblastoma multiforme.

Authors:  S E Vogl
Journal:  Cancer       Date:  1978-01       Impact factor: 6.860

2.  Brief communication: Pathologic effects in rats surviving prenatal and neonatal administration of 1,3-bis(2-chloroethyl)-1-nitrosourea.

Authors:  E de C Weiss; H Cravioto; J F Weiss; J Ransohoff
Journal:  J Natl Cancer Inst       Date:  1973-10       Impact factor: 13.506

3.  Genotypes and phenotypes of ten inbred strains of BD-rats.

Authors:  H Druckrey
Journal:  Arzneimittelforschung       Date:  1971-08

4.  Chemotherapeutic activity of new 2-chloroethylnitrosoureas in rat L5222 leukemia: comparison of bifunctional and water-soluble derivatives with 1,3-bis(2-chloroethyl)-1-nitrosourea.

Authors:  W J Zeller; G Eisenbrand; H H Fiebig
Journal:  J Natl Cancer Inst       Date:  1978-02       Impact factor: 13.506

5.  Acute nonlymphocytic leukemia associated with nitrosourea chemotherapy: report of two cases.

Authors:  R J Cohen; P H Wiernik; M D Walker
Journal:  Cancer Treat Rep       Date:  1976-09
  5 in total
  1 in total

1.  Autopsy Analysis may Contribute to Establish Actual Incidence of Second Primary Malignancies in Myeloma.

Authors:  Junichiro Takano; Shotaro Hagiwara; Akiyoshi Miwa
Journal:  Rare Tumors       Date:  2015-12-29
  1 in total

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