BACKGROUND: Stent blockage is a multifactorial process in which stent design and materials, bacteria, proteins, and bile viscosity play a role. AIMS: To compare the patency of the 10 Fr Teflon Tannenbaum (TT) stent to that of the 10 Fr Cotton-Leung (CL) polyethylene stent with sideholes, in patients with malignant obstructive jaundice. METHODS: Patients were recruited to this prospective multicentre randomised study if they had a newly diagnosed malignant bile duct stricture below the hilum of the liver suitable for stenting with a 10 Fr stent. Data were collected and monitored by a professional monitoring company. Primary patency was the interval between stent placement and first exchange or death without recurrent jaundice. RESULTS:134 consecutive patients were recruited between November 1994 and June 1997; 65 were randomised to the TT stent and 69 to the CL stent. Median patency and 95% confidence intervals were 181 (59, 303) days for the TT stent and 133 (92, 174) days for the CL stent, with no significant difference between the two stents (p=0.49). Median survival and 95% confidence intervals were 115 (71, 159) days for the TT stent and 151 (112, 190) days for the CL stent, with no significant difference between the two stents (p=0.765). CONCLUSION: Neither Teflon as a stent material nor the Tannenbaum design prolong the patency of plastic stents.
RCT Entities:
BACKGROUND: Stent blockage is a multifactorial process in which stent design and materials, bacteria, proteins, and bile viscosity play a role. AIMS: To compare the patency of the 10 Fr Teflon Tannenbaum (TT) stent to that of the 10 Fr Cotton-Leung (CL) polyethylene stent with sideholes, in patients with malignant obstructive jaundice. METHODS:Patients were recruited to this prospective multicentre randomised study if they had a newly diagnosed malignant bile duct stricture below the hilum of the liver suitable for stenting with a 10 Fr stent. Data were collected and monitored by a professional monitoring company. Primary patency was the interval between stent placement and first exchange or death without recurrent jaundice. RESULTS: 134 consecutive patients were recruited between November 1994 and June 1997; 65 were randomised to the TT stent and 69 to the CL stent. Median patency and 95% confidence intervals were 181 (59, 303) days for the TT stent and 133 (92, 174) days for the CL stent, with no significant difference between the two stents (p=0.49). Median survival and 95% confidence intervals were 115 (71, 159) days for the TT stent and 151 (112, 190) days for the CL stent, with no significant difference between the two stents (p=0.765). CONCLUSION: Neither Teflon as a stent material nor the Tannenbaum design prolong the patency of plastic stents.
Authors: A M van Berkel; C Boland; W K Redekop; J J Bergman; A K Groen; G N Tytgat; K Huibregtse Journal: Endoscopy Date: 1998-10 Impact factor: 10.093
Authors: Petra G A van Boeckel; Ewout W Steyerberg; Frank P Vleggaar; Marcel J M Groenen; Ben J M Witteman; Bas L A M Weusten; Han Geldof; Adriaan C I T L Tan; Marina J A L Grubben; Jan Nicolai; Peter D Siersema Journal: J Gastroenterol Date: 2011-07-14 Impact factor: 7.527
Authors: P Katsinelos; D Paikos; J Kountouras; G Chatzimavroudis; G Paroutoglou; I Moschos; A Gatopoulou; A Beltsis; C Zavos; B Papaziogas Journal: Surg Endosc Date: 2006-08-07 Impact factor: 4.584
Authors: Mouen A Khashab; Susan Hutfless; Katherine Kim; Anne Marie Lennon; Marcia I Canto; Sanjay B Jagannath; Patrick I Okolo; Eun Ji Shin; Vikesh K Singh Journal: Dig Dis Sci Date: 2012-01-20 Impact factor: 3.199
Authors: Chang-Il Kwon; Mark A Gromski; Stuart Sherman; Jeffrey J Easler; Ihab I El Hajj; James Watkins; Evan L Fogel; Lee McHenry; Glen A Lehman Journal: Dig Dis Sci Date: 2016-05-06 Impact factor: 3.199