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Literature DB >> 10671901

Drug trials in children: problems and the way forward.

S Conroy¹, J McIntyre, I Choonara, T Stephenson.

Abstract

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Year: 2000 PMID： 10671901 PMCID： PMC2014901 DOI： 10.1046/j.1365-2125.2000.00125.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

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25 in total

1. Urinary excretion of 6 beta-hydroxycortisol and the time course measurement of enzyme induction in man.

Authors: E E Ohnhaus; A M Breckenridge; B K Park
Journal: Eur J Clin Pharmacol Date: 1989 Impact factor: 2.953

2. Tenfold errors in administration of drug doses: a neglected iatrogenic disease in pediatrics.

Authors: G Koren; Z Barzilay; M Greenwald
Journal: Pediatrics Date: 1986-06 Impact factor: 7.124

3. Use of "off-label" and unlicensed drugs in paediatric intensive care unit.

Authors: S Turner; A Gill; T Nunn; B Hewitt; I Choonara
Journal: Lancet Date: 1996-02-24 Impact factor: 79.321

Review 4. Paracetamol poisoning in children and hepatotoxicity.

Authors: A Penna; N Buchanan
Journal: Br J Clin Pharmacol Date: 1991-08 Impact factor: 4.335

5. Population pharmacokinetics of midazolam in neonates.

Authors: P Burtin; E Jacqz-Aigrain; P Girard; R Lenclen; J F Magny; P Betremieux; C Tehiry; L Desplanques; P Mussat
Journal: Clin Pharmacol Ther Date: 1994-12 Impact factor: 6.875

6. Morphine metabolism in neonates and infants.

Authors: I Choonara; A Lawrence; A Michalkiewicz; A Bowhay; J Ratcliffe
Journal: Br J Clin Pharmacol Date: 1992-11 Impact factor: 4.335

7. Valproate metabolites in serum and urine during antiepileptic therapy in children with infantile spasms: abnormal metabolite pattern associated with reversible hepatotoxicity.

Authors: E Fisher; H Siemes; R Pund; W Wittfoht; H Nau
Journal: Epilepsia Date: 1992 Jan-Feb Impact factor: 5.864

8. A prospective study of the adverse effects of midazolam on withdrawal in critically ill children.

Authors: J Hughes; A Gill; H J Leach; A J Nunn; I Billingham; J Ratcliffe; R Thornington; I Choonara
Journal: Acta Paediatr Date: 1994-11 Impact factor: 2.299

9. Lorazepam versus diazepam in the acute treatment of epileptic seizures and status epilepticus.

Authors: R Appleton; A Sweeney; I Choonara; J Robson; E Molyneux
Journal: Dev Med Child Neurol Date: 1995-08 Impact factor: 5.449

10. Inhibition of caffeine metabolism by ciprofloxacin in children with cystic fibrosis as measured by the caffeine breath test.

Authors: A C Parker; T Preston; D Heaf; N R Kitteringham; I Choonara
Journal: Br J Clin Pharmacol Date: 1994-12 Impact factor: 4.335

29 in total

1. Investigating allegations of research misconduct. Worst outcome of Griffiths report would be that research becomes increasingly difficult.

Authors: T Stephenson
Journal: BMJ Date: 2000-11-25

2. Clinical trials of medicines in children.

Authors: I Choonara
Journal: BMJ Date: 2000-11-04

Review 3. Medicines for children--the last century and the next.

Authors: T Stephenson
Journal: Arch Dis Child Date: 2001-09 Impact factor: 3.791

4. Off-label antibiotic use in children in three European countries.

Authors: Alessandro Porta; Susanna Esposito; Esse Menson; Nikos Spyridis; Maria Tsolia; Mike Sharland; Nicola Principi
Journal: Eur J Clin Pharmacol Date: 2010-06-08 Impact factor: 2.953

Review 5. Dose estimation for children.

Authors: Nigel Baber; Deborah Pritchard
Journal: Br J Clin Pharmacol Date: 2003-11 Impact factor: 4.335

Review 9. Clinical trials in children.

Authors: Pathma D Joseph; Jonathan C Craig; Patrina H Y Caldwell
Journal: Br J Clin Pharmacol Date: 2015-03 Impact factor: 4.335

10. Drug trials in children: Doubts and dilemmas.

Authors: Bharat Dalvi
Journal: Ann Pediatr Cardiol Date: 2008-07