| Literature DB >> 1066689 |
K Mortelmans, E C Friedberg, H Slor, G Thomas, J E Cleaver.
Abstract
Crude extracts of normal human diploid fibroblasts and of human peripheral blood lymphocytes excise thymine dimers from purified ultraviolet-irradiated DNA, or from the DNA presumably present as chromatin in unfractionated cell-free preparations of cells that had been labeled with [3H]thymidine. Extracts of xeroderma pigmentosum cells from complementation groups A, C, and D also excise thymine dimers from purified DNA, but extracts of group A cells do not excise dimers from the DNA of radioactively labeled unfractionated cell-free preparations.Entities:
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Year: 1976 PMID: 1066689 PMCID: PMC430730 DOI: 10.1073/pnas.73.8.2757
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205