Literature DB >> 1066689

Defective thymine dimer excision by cell-free extracts of xeroderma pigmentosum cells.

K Mortelmans, E C Friedberg, H Slor, G Thomas, J E Cleaver.   

Abstract

Crude extracts of normal human diploid fibroblasts and of human peripheral blood lymphocytes excise thymine dimers from purified ultraviolet-irradiated DNA, or from the DNA presumably present as chromatin in unfractionated cell-free preparations of cells that had been labeled with [3H]thymidine. Extracts of xeroderma pigmentosum cells from complementation groups A, C, and D also excise thymine dimers from purified DNA, but extracts of group A cells do not excise dimers from the DNA of radioactively labeled unfractionated cell-free preparations.

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Year:  1976        PMID: 1066689      PMCID: PMC430730          DOI: 10.1073/pnas.73.8.2757

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  26 in total

1.  The effect of a mammalian repair endonuclease on x-irradiated DNA.

Authors:  T Tomura; J L van Lancker
Journal:  Biochim Biophys Acta       Date:  1975-09-01

2.  Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates.

Authors:  K H Kraemer; H G Coon; R A Petinga; S F Barrett; A E Rahe; J H Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Restoration of ultraviolet-induced unscheduled DNA synthesis of xeroderma pigmentosum cells by the concomitant treatment with bacteriophage T4 endonuclease V and HVJ (Sendai virus).

Authors:  K Tanaka; M Sekiguchi; Y Okada
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

4.  Five complementation groups in xeroderma pigmentosum.

Authors:  K H Kraemer; E A De Weerd-Kastelein; J H Robbins; W Keijzer; S F Barrett; R A Petinga; D Bootsma
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

5.  Purification and characterization of an endonuclease from calf thymus acting on irradiated DNA.

Authors:  S Bacchetti; R Benne
Journal:  Biochim Biophys Acta       Date:  1975-05-16

6.  DNA single-strand breaks during repair of UV damage in human fibroblasts and abnormalities of repair in xeroderma pigmentosum.

Authors:  A J Fornace; K W Kohn; H E Kann
Journal:  Proc Natl Acad Sci U S A       Date:  1976-01       Impact factor: 11.205

7.  Purification and some properties of a mammalian repair endonuclease.

Authors:  J L van Lancker; T Tomura
Journal:  Biochim Biophys Acta       Date:  1974-06-14

8.  A UV-specific endonucleolytic activity present in human cell extracts.

Authors:  S Bacchetti; A van der Plas; G Veldhuisen
Journal:  Biochem Biophys Res Commun       Date:  1972-08-07       Impact factor: 3.575

9.  Genetic heterogeneity of xeroderma pigmentosum demonstrated by somatic cell hybridization.

Authors:  E A De Weerd-Kastelein; W Keijzer; D Bootsma
Journal:  Nat New Biol       Date:  1972-07-19

10.  Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair.

Authors:  J H Robbins; K H Kraemer; M A Lutzner; B W Festoff; H G Coon
Journal:  Ann Intern Med       Date:  1974-02       Impact factor: 25.391

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  35 in total

Review 1.  Human DNA repair defects.

Authors:  C F Arlett
Journal:  J Inherit Metab Dis       Date:  1986       Impact factor: 4.982

2.  Domains in the XPA protein important in its role as a processivity factor.

Authors:  Claudine L Bartels; Muriel W Lambert
Journal:  Biochem Biophys Res Commun       Date:  2007-03-02       Impact factor: 3.575

3.  A cell-free assay measuring repair DNA synthesis in human fibroblasts.

Authors:  G Ciarrocchi; S Linn
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

4.  Cells from an immunodeficient patient (46BR) with a defect in DNA ligation are hypomutable but hypersensitive to the induction of sister chromatid exchanges.

Authors:  L M Henderson; C F Arlett; S A Harcourt; A R Lehmann; B C Broughton
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

5.  Repair of UV-induced lesions in Xenopus laevis oocytes.

Authors:  R J Legerski; J E Penkala; C A Peterson; D A Wright
Journal:  Mol Cell Biol       Date:  1987-12       Impact factor: 4.272

6.  Defective thymine dimer excision in radiation-sensitive mutants rad10 and rad16 of Saccharomyces cerevisiae.

Authors:  L Prakash
Journal:  Mol Gen Genet       Date:  1977-04-29

7.  Isolation and characterization of monoclonal antibodies directed against the DNA repair enzyme uracil DNA glycosylase from human placenta.

Authors:  P Arenaz; M A Sirover
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

8.  DNA repair in Cockayne syndrome.

Authors:  D I Hoar; C Waghorne
Journal:  Am J Hum Genet       Date:  1978-11       Impact factor: 11.025

9.  Purification of PCNA as a nucleotide excision repair protein.

Authors:  A F Nichols; A Sancar
Journal:  Nucleic Acids Res       Date:  1992-07-11       Impact factor: 16.971

10.  Association of poly(adenosine diphosphoribose) synthesis with DNA damage and repair in normal human lymphocytes.

Authors:  N A Berger; G W Sikorski; S J Petzold; K K Kurohara
Journal:  J Clin Invest       Date:  1979-06       Impact factor: 14.808

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