Literature DB >> 1065896

Deficiency of gamma-ray excision repair in skin fibroblasts from patients with Fanconi's anemia.

J F Remsen, P A Cerutti.   

Abstract

The capacity of preparations of skin fibroblasts from normal individuals and patients with Fanconi's anemia to excise gamma-ray products of the 5,6-dihydroxydihydrothymine type from exogenous DNA was investigated. The excision capacity of whole-cell homogenates of fibroblasts from two of four patients with Fanconi's anemia was substantially below normal. This repair deficiency was further pronounced in nuclear preparations from cells of the same two patients.

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Year:  1976        PMID： 1065896      PMCID： PMC430591          DOI： 10.1073/pnas.73.7.2419

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  19 in total

1.  Strand breakage of coliphage lambda DNA supercoils in infected lysogens. I. Genetic and biochemical evidence for two types of nicking processes.

Authors:  R McMacken; S Kessler; R Boyce
Journal:  Virology       Date:  1975-08       Impact factor: 3.616

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Purification and characterization of an endonuclease from calf thymus acting on irradiated DNA.

Authors:  S Bacchetti; R Benne
Journal:  Biochim Biophys Acta       Date:  1975-05-16

4.  Purification and some properties of a mammalian repair endonuclease.

Authors:  J L van Lancker; T Tomura
Journal:  Biochim Biophys Acta       Date:  1974-06-14

5.  Nuclease for DNA apurinic sites may be involved in the maintenance of DNA in normal cells.

Authors:  W G Verly; Y Paquette; L Thibodeau
Journal:  Nat New Biol       Date:  1973-07-18

6.  A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.

Authors:  M S Sasaki; A Tonomura
Journal:  Cancer Res       Date:  1973-08       Impact factor: 12.701

7.  Defective DNA repair in Fanconi's anaemia.

Authors:  P K Poon; R L O'Brien; J W Parker
Journal:  Nature       Date:  1974-07-19       Impact factor: 49.962

8.  Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification.

Authors:  K R Yamamoto; B M Alberts; R Benzinger; L Lawhorne; G Treiber
Journal:  Virology       Date:  1970-03       Impact factor: 3.616

9.  Mycoplasma contamination of animal cell cultures: a simple, rapid detection method.

Authors:  E M Levine
Journal:  Exp Cell Res       Date:  1972-09       Impact factor: 3.905

10.  Excision of damaged thymine residues from gamma-irradiated poly(dA-dT) by crude extracts of Escherichia coli.

Authors:  P V Hariharan; P A Cerutti
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205
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  18 in total

Review 1.  Genetic and biochemical studies with ataxia telangiectasia. A review.

Authors:  P C Huang; R B Sheridan
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

Review 2.  Human DNA repair defects.

Authors:  C F Arlett
Journal:  J Inherit Metab Dis       Date:  1986       Impact factor: 4.982

3.  Fanconi anemia mutation causes cellular susceptibility to ambient oxygen.

Authors:  D Schindler; H Hoehn
Journal:  Am J Hum Genet       Date:  1988-10       Impact factor: 11.025

4.  Antagonistic effect of cocultivation on mitomycin C-induced aberration rate in cells of a patient with Fanconi's anemia and in Chinese hamster ovary cells.

Authors:  S Zakrzewski; K Sperling
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

5.  Characteristics of excision repair of pyrimidine dimers in eukaryotic cells as assayed with anti-dimer sera.

Authors:  J J Cornelis
Journal:  Nucleic Acids Res       Date:  1978-11       Impact factor: 16.971

6.  Complementation studies between Fanconi's anemia cells with different DNA repair characteristics.

Authors:  S Zakrzewski; M Koch; K Sperling
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

7.  UV-repair is impaired in fibroblasts from patients with Fanconi's anemia.

Authors:  H Schwaiger; M Hirsch-Kauffmann; M Schweiger
Journal:  Mol Gen Genet       Date:  1982

8.  DNA semi-conservative synthesis in normal and Fanconi anemia fibroblasts following treatment with 8-methoxypsoralen and near ultraviolet light or with X-rays.

Authors:  E Moustacchi; C Diatloff-Zito
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

9.  Chromatid damage after G2 phase x-irradiation of cells from cancer-prone individuals implicates deficiency in DNA repair.

Authors:  R Parshad; K K Sanford; G M Jones
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

10.  Mutagenic effects of isonicotinic acid hydracide in Fanconi's anemia.

Authors:  T M Schroeder; C Stahl-Maugé
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132
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