Literature DB >> 10654417

Oceanapiside, an antifungal bis-alpha,omega-amino alcohol glycoside from the marine sponge Oceanapia phillipensis.

G M Nicholas1, T W Hong, T F Molinski, M L Lerch, M T Cancilla, C B Lebrilla.   

Abstract

The structure of oceanapiside, an antifungal alpha, omega-bis-aminohydroxylipid glycoside from the temperate marine sponge Oceanapia sp., was elucidated by a combination of 2D NMR, chemical degradation/correlation, and MALDI MS-MS spectrometry. Oceanapiside exhibits antifungal activity against Candida glabrata at 10 micrograms/mL (MIC).

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Year:  1999        PMID： 10654417     DOI： 10.1021/np990190v

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  20 in total

1.  Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine.

Authors:  Colin K Skepper; Doralyn S Dalisay; Tadeusz F Molinski
Journal:  Bioorg Med Chem Lett       Date:  2010-02-01       Impact factor: 2.823

2.  INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS.

Authors:  Tadeusz F Molinski; Brandon I Morinaka
Journal:  Tetrahedron       Date:  2012-11-18       Impact factor: 2.457

Review 3.  Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis.

Authors:  Takashi L Suyama; William H Gerwick; Kerry L McPhail
Journal:  Bioorg Med Chem       Date:  2011-06-12       Impact factor: 3.641

4.  Isorhizochalin: a minor unprecedented bipolar sphingolipid of stereodivergent biogenesis from the Rhizochalina incrustata.

Authors:  Tatyana N Makarieva; Alexander M Zakharenko; Pavel S Dmitrenok; Alla G Guzii; Vladimir A Denisenko; Alexandra S Savina; Doralyn S Dalisay; Tadeusz F Molinski; Valentin A Stonik
Journal:  Lipids       Date:  2009-10-30       Impact factor: 1.880

5.  Zwittermicin A: synthesis of analogs and structure-activity studies.

Authors:  Evan W Rogers; Doralyn S Dalisay; Tadeusz F Molinski
Journal:  Bioorg Med Chem Lett       Date:  2010-02-11       Impact factor: 2.823

6.  Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans.

Authors:  Doralyn S Dalisay; Jonel P Saludes; Tadeusz F Molinski
Journal:  Bioorg Med Chem       Date:  2011-05-27       Impact factor: 3.641

7.  Marine two-headed sphingolipid-like compound rhizochalin inhibits EGF-induced transformation of JB6 P+ Cl41 cells.

Authors:  Sergey N Fedorov; Tatyana N Makarieva; Alla G Guzii; Larisa K Shubina; Jong Y Kwak; Valentin A Stonik
Journal:  Lipids       Date:  2009-07-05       Impact factor: 1.880

Review 8.  Drug targets in mycobacterial sulfur metabolism.

Authors:  Devayani P Bhave; Wilson B Muse; Kate S Carroll
Journal:  Infect Disord Drug Targets       Date:  2007-06

9.  Absolute configuration of the alpha,omega-bifunctionalized sphingolipid leucettamol A from Leucetta microrhaphis by deconvoluted exciton coupled CD.

Authors:  Doralyn S Dalisay; Sachiko Tsukamoto; Tadeusz F Molinski
Journal:  J Nat Prod       Date:  2009-03-27       Impact factor: 4.050

Review 10.  Glycosides from marine sponges (Porifera, Demospongiae): structures, taxonomical distribution, biological activities and biological roles.

Authors:  Vladimir I Kalinin; Natalia V Ivanchina; Vladimir B Krasokhin; Tatyana N Makarieva; Valentin A Stonik
Journal:  Mar Drugs       Date:  2012-08-10       Impact factor: 6.085
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