Literature DB >> 10615891

Hypocretin (orexin) deficiency in human narcolepsy.

S Nishino, B Ripley, S Overeem, G J Lammers, E Mignot.   

Abstract

Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was undetectable in seven out of nine people with narcolepsy, indicating abnormal hypocretin transmission.

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Year:  2000        PMID： 10615891     DOI： 10.1016/S0140-6736(99)05582-8

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  401 in total

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Journal:  J Neurosci       Date:  2000-10-15       Impact factor: 6.167

Review 2.  The sleepy patient.

Authors:  N J Douglas
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3.  What we learned from narcolepsy of others.

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Journal:  J Mol Med (Berl)       Date:  2003-02       Impact factor: 4.599

4.  Excessive daytime somnolence and increased rapid eye movement pressure in myotonic dystrophy.

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5.  Sleep disturbances in adult survivors of childhood brain tumors.

Authors:  Vikki G Nolan; Roxanna Gapstur; Cynthia R Gross; Lauren A Desain; Joseph P Neglia; Amar Gajjar; James L Klosky; Thomas E Merchant; Marilyn Stovall; Kirsten K Ness
Journal:  Qual Life Res       Date:  2012-06-06       Impact factor: 4.147

6.  Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women.

Authors:  Gregory J Tranah; Terri Blackwell; Katie L Stone; Sonia Ancoli-Israel; Misti L Paudel; Kristine E Ensrud; Jane A Cauley; Susan Redline; Teresa A Hillier; Steven R Cummings; Kristine Yaffe
Journal:  Ann Neurol       Date:  2011-11       Impact factor: 10.422

7.  Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus.

Authors:  X B Gao; A N van den Pol
Journal:  J Physiol       Date:  2001-05-15       Impact factor: 5.182

8.  Low CSF hypocretin-1/orexin-A associated with hypersomnia secondary to hypothalamic lesion in a case of multiple sclerosis.

Authors:  Yasunori Oka; Takashi Kanbayashi; Takahiro Mezaki; Kazumi Iseki; Jun Matsubayashi; Gaku Murakami; Masaru Matsui; Tetsuo Shimizu; Hiroshi Shibasaki
Journal:  J Neurol       Date:  2004-07       Impact factor: 4.849

9.  CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome.

Authors:  Takashi Kanbayashi; Tohru Kodama; Hideaki Kondo; Shinsuke Satoh; Yuichi Inoue; Shigeru Chiba; Tetsuo Shimizu; Seiji Nishino
Journal:  Sleep       Date:  2009-02       Impact factor: 5.849

10.  Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls.

Authors:  Seiji Nishino; Eiko Sakurai; Sona Nevsimalova; Yasushi Yoshida; Takehiko Watanabe; Kazuhiko Yanai; Emmanuel Mignot
Journal:  Sleep       Date:  2009-02       Impact factor: 5.849
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