PURPOSE: The aims of this study are to compare self-reported sleep quality in adult survivors of childhood brain tumors and a population-based comparison group, to identify treatment-related factors associated with sleep disturbances, and to identify the impact of post-treatment obesity and depression on sleep scores in adult survivors of childhood brain tumors. METHODS: Randomly selected adult survivors of childhood brain tumors (n = 78) and age-, sex-, and zip code-matched population-group members (n = 78) completed the Pittsburgh Sleep Quality Index and the Brief Symptom Inventory. Sleep quality and the effect of demographic, treatment, and post-treatment characteristics were evaluated with linear and logistic regression analyses. RESULTS: Brain tumor survivors were 2.7 (95% CI, 1.1, 6.5) times more likely than the comparison group to take greater than 30 min to fall asleep. Females in both groups reported worse sleep quality and impaired daytime functioning. Among survivors, post-treatment obesity was associated with daytime dysfunction. CONCLUSIONS: These results agree with previous studies associating sleep, sex, and obesity and identified longer sleep latency as being a problem among childhood brain tumor survivors. Further study identifying factors contributing to sleep latency, and its impact on quality of life among adult survivors of childhood brain tumors is needed.
PURPOSE: The aims of this study are to compare self-reported sleep quality in adult survivors of childhood brain tumors and a population-based comparison group, to identify treatment-related factors associated with sleep disturbances, and to identify the impact of post-treatment obesity and depression on sleep scores in adult survivors of childhood brain tumors. METHODS: Randomly selected adult survivors of childhood brain tumors (n = 78) and age-, sex-, and zip code-matched population-group members (n = 78) completed the Pittsburgh Sleep Quality Index and the Brief Symptom Inventory. Sleep quality and the effect of demographic, treatment, and post-treatment characteristics were evaluated with linear and logistic regression analyses. RESULTS:Brain tumor survivors were 2.7 (95% CI, 1.1, 6.5) times more likely than the comparison group to take greater than 30 min to fall asleep. Females in both groups reported worse sleep quality and impaired daytime functioning. Among survivors, post-treatment obesity was associated with daytime dysfunction. CONCLUSIONS: These results agree with previous studies associating sleep, sex, and obesity and identified longer sleep latency as being a problem among childhood brain tumor survivors. Further study identifying factors contributing to sleep latency, and its impact on quality of life among adult survivors of childhood brain tumors is needed.
Authors: Andrea Poretti; Michael A Grotzer; Karin Ribi; Eugen Schönle; Eugen Boltshauser Journal: Dev Med Child Neurol Date: 2004-04 Impact factor: 5.449
Authors: Melissa M Hudson; Ann C Mertens; Yutaka Yasui; Wendy Hobbie; Hegang Chen; James G Gurney; Mark Yeazel; Christopher J Recklitis; Neyssa Marina; Leslie R Robison; Kevin C Oeffinger Journal: JAMA Date: 2003-09-24 Impact factor: 157.335
Authors: Deborah B Crom; Zhenghong Li; Tara M Brinkman; Melissa M Hudson; Gregory T Armstrong; Joseph Neglia; Kirsten K Ness Journal: J Pediatr Oncol Nurs Date: 2014-07-15 Impact factor: 1.636
Authors: Ineke M Olsthoorn; Alice Ann Holland; Raymond C Hawkins; Allen E Cornelius; Muhammad Usman Baig; Grace Yang; Daniel C Holland; Wafik Zaky; Peter L Stavinoha Journal: Front Neurosci Date: 2022-06-23 Impact factor: 5.152
Authors: Raja B Khan; Thomas E Merchant; Zsila S Sadighi; Mercedes S Bello; Zhaohua Lu; April Sykes; Merrill S Wise; Valerie M Crabtree; Jennifer Zabrowski; Andrea Simmons; Mary E Clark; Belinda N Mandrell Journal: J Neurooncol Date: 2017-11-08 Impact factor: 4.130
Authors: Lisa M Jacola; Heather M Conklin; Matthew A Scoggins; Jason M Ashford; Thomas E Merchant; Belinda N Mandrell; Robert J Ogg; Elizabeth Curtis; Merrill S Wise; Daniel J Indelicato; Valerie M Crabtree Journal: J Pediatr Psychol Date: 2016-05-16