Literature DB >> 10600721

Aminoglycoside-RNA interactions.

F Walter1, Q Vicens, E Westhof.   

Abstract

The structural and physico-chemical parameters promoting the binding of aminoglycosides to RNAs are becoming clear. The strength of the interaction is dominated by electrostatics, with the positively charged aminoglycosides displacing metal ions. Although aminoglycosides inhibit most known ribozymes, aminoglycosides or polyamines are able to catalyze specific RNA cleavage in the absence of metal ions.

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Year:  1999        PMID： 10600721     DOI： 10.1016/s1367-5931(99)00028-9

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  56 in total

1.  Kinetics of inhibition of ribonuclease P activity by peptidyltransferase inhibitors. Effect of antibiotics on RNase P.

Authors:  Dimitra Kalavrizioti; Anastassios Vourekas; Apostolos Tekos; Antigoni Tsagla; Constantinos Stathopoulos; Denis Drainas
Journal:  Mol Biol Rep       Date:  2003-03       Impact factor: 2.316

2.  Inhibition of protein synthesis by aminoglycoside-arginine conjugates.

Authors:  Marjolaine Carriere; Veerappan Vijayabaskar; Drew Applefield; Isabelle Harvey; Philippe Garneau; Jon Lorsch; Aviva Lapidot; Jerry Pelletier
Journal:  RNA       Date:  2002-10       Impact factor: 4.942

Review 3.  Aminoglycoside antibiotics: structure, functions and effects on in vitro plant culture and genetic transformation protocols.

Authors:  I M G Padilla; L Burgos
Journal:  Plant Cell Rep       Date:  2010-07-20       Impact factor: 4.570

4.  Screening for engineered neomycin riboswitches that control translation initiation.

Authors:  Julia E Weigand; Martin Sanchez; Ewald-Bernd Gunnesch; Sabrina Zeiher; Renee Schroeder; Beatrix Suess
Journal:  RNA       Date:  2007-11-13       Impact factor: 4.942

Review 5.  Inhibition of bacterial ribosome assembly: a suitable drug target?

Authors:  Bruce A Maguire
Journal:  Microbiol Mol Biol Rev       Date:  2009-03       Impact factor: 11.056

6.  Association of aminoglycosidic antibiotics with the ribosomal A-site studied with Brownian dynamics.

Authors:  Maciej Długosz; Jan M Antosiewicz; Joanna Trylska
Journal:  J Chem Theory Comput       Date:  2008-04       Impact factor: 6.006

7.  [Start codon in the serine proteinase gene from Bacillus intermedius].

Authors:  A R Kaiumov; A R Sabirova; N P Balaban; A M Mardanova; O N Il'inskaia; S V Kostrov; M R Sharipova
Journal:  Mol Biol (Mosk)       Date:  2008 Jan-Feb

8.  Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis.

Authors:  Subramanian Akshay; Mihai Bertea; Sven N Hobbie; Björn Oettinghaus; Dimitri Shcherbakov; Erik C Böttger; Rashid Akbergenov
Journal:  Antimicrob Agents Chemother       Date:  2011-07-05       Impact factor: 5.191

9.  Two-dimensional combinatorial screening identifies specific 6'-acylated kanamycin A- and 6'-acylated neamine-RNA hairpin interactions.

Authors:  Olga Aminova; Dustin J Paul; Jessica L Childs-Disney; Matthew D Disney
Journal:  Biochemistry       Date:  2008-12-02       Impact factor: 3.162

10.  Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis.

Authors:  Md Alamgir; Veronika Eroukova; Matthew Jessulat; Jianhua Xu; Ashkan Golshani
Journal:  BMC Genomics       Date:  2008-12-03       Impact factor: 3.969
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