Literature DB >> 10557159

Nucleic acid molecular switches.

G A Soukup1, R R Breaker.   

Abstract

Natural and artificial ribozymes can catalyse a diverse range of chemical reactions. Through recent efforts in enzyme engineering, it has become possible to tailor the activity of ribozymes to respond allosterically to specific effector compounds. These allosteric ribozymes function as effector-dependent molecular switches that could find application as novel genetic-control elements, biosensor components or precision switches for use in nanotechnology.

Mesh：

Substances：

Year:  1999        PMID： 10557159     DOI： 10.1016/s0167-7799(99)01383-9

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN： 0167-7799            Impact factor:   19.536


  35 in total

1.  Cooperative binding of effectors by an allosteric ribozyme.

Authors:  A M Jose; G A Soukup; R R Breaker
Journal:  Nucleic Acids Res       Date:  2001-04-01       Impact factor: 16.971

Review 2.  Chemical approaches to control gene expression.

Authors:  J M Gottesfeld; J M Turner; P B Dervan
Journal:  Gene Expr       Date:  2000

3.  Homogeneous assays based on deoxyribozyme catalysis.

Authors:  M N Stojanovic; P de Prada; D W Landry
Journal:  Nucleic Acids Res       Date:  2000-08-01       Impact factor: 16.971

4.  A general approach for the use of oligonucleotide effectors to regulate the catalysis of RNA-cleaving ribozymes and DNAzymes.

Authors:  Dennis Y Wang; Beatrice H Y Lai; Anat R Feldman; Dipankar Sen
Journal:  Nucleic Acids Res       Date:  2002-04-15       Impact factor: 16.971

5.  Optimization and optimality of a short ribozyme ligase that joins non-Watson-Crick base pairings.

Authors:  M P Robertson; J R Hesselberth; A D Ellington
Journal:  RNA       Date:  2001-04       Impact factor: 4.942

6.  A biosensor for theophylline based on fluorescence detection of ligand-induced hammerhead ribozyme cleavage.

Authors:  Phillip T Sekella; David Rueda; Nils G Walter
Journal:  RNA       Date:  2002-10       Impact factor: 4.942

7.  Exploring the repertoire of RNA secondary motifs using graph theory; implications for RNA design.

Authors:  Hin Hark Gan; Samuela Pasquali; Tamar Schlick
Journal:  Nucleic Acids Res       Date:  2003-06-01       Impact factor: 16.971

Review 8.  Rube Goldberg goes (ribo)nuclear? Molecular switches and sensors made from RNA.

Authors:  Scott K Silverman
Journal:  RNA       Date:  2003-04       Impact factor: 4.942

9.  Kinetic analysis of aptazyme-regulated gene expression in a cell-free translation system: modeling of ligand-dependent and -independent expression.

Authors:  Shungo Kobori; Norikazu Ichihashi; Yasuaki Kazuta; Tomoaki Matsuura; Tetsuya Yomo
Journal:  RNA       Date:  2012-06-25       Impact factor: 4.942

10.  Computational approaches toward the design of pools for the in vitro selection of complex aptamers.

Authors:  Xuemei Luo; Maureen McKeague; Sylvain Pitre; Michel Dumontier; James Green; Ashkan Golshani; Maria C Derosa; Frank Dehne
Journal:  RNA       Date:  2010-09-24       Impact factor: 4.942
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.