Literature DB >> 10498206

Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.

M L Greenlee1, J B Laub, J M Balkovec, M L Hammond, G G Hammond, D L Pompliano, J H Epstein-Toney.   

Abstract

Potent thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase have been synthesized employing a solid-phase Mitsunobu reaction as the key step.

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Year:  1999        PMID： 10498206     DOI： 10.1016/s0960-894x(99)00425-4

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  Inhibition of beta-lactamase II of Bacillus cereus by penamaldic derivatives of penicillins.

Authors:  Pilar Gutiérrez Navarro; Bartolomé Quintero Osso; Raquel García Ortiz; Pedro J Martínez De Las Parras; María I Martínez Puentedura; M Carmen Cabeza González
Journal:  Antimicrob Agents Chemother       Date:  2004-03       Impact factor: 5.191

Review 2.  A close look onto structural models and primary ligands of metallo-β-lactamases.

Authors:  Joanna E Raczynska; Ivan G Shabalin; Wladek Minor; Alexander Wlodawer; Mariusz Jaskolski
Journal:  Drug Resist Updat       Date:  2018-08-25       Impact factor: 18.500

Review 3.  Metallo-beta-lactamases: the quiet before the storm?

Authors:  Timothy R Walsh; Mark A Toleman; Laurent Poirel; Patrice Nordmann
Journal:  Clin Microbiol Rev       Date:  2005-04       Impact factor: 26.132

4.  Amino Acid Thioester Derivatives: A Highly Promising Scaffold for the Development of Metallo-β-lactamase L1 Inhibitors.

Authors:  Xiao-Long Liu; Ying Shi; Joon S Kang; Peter Oelschlaeger; Ke-Wu Yang
Journal:  ACS Med Chem Lett       Date:  2015-04-23       Impact factor: 4.345

5.  Biochemical characterization of the FEZ-1 metallo-beta-lactamase of Legionella gormanii ATCC 33297T produced in Escherichia coli.

Authors:  P S Mercuri; F Bouillenne; L Boschi; J Lamotte-Brasseur; G Amicosante; B Devreese; J van Beeumen; J M Frère; G M Rossolini; M Galleni
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

6.  N-arylsulfonyl hydrazones as inhibitors of IMP-1 metallo-beta-lactamase.

Authors:  Stefan Siemann; Darryl P Evanoff; Laura Marrone; Anthony J Clarke; Thammaiah Viswanatha; Gary I Dmitrienko
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

Review 7.  Diversity and Proliferation of Metallo-β-Lactamases: a Clarion Call for Clinically Effective Metallo-β-Lactamase Inhibitors.

Authors:  Anou M Somboro; John Osei Sekyere; Daniel G Amoako; Sabiha Y Essack; Linda A Bester
Journal:  Appl Environ Microbiol       Date:  2018-08-31       Impact factor: 4.792

8.  An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases.

Authors:  Nazar Ul Islam
Journal:  Sci Pharm       Date:  2013-03-28

9.  Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid.

Authors:  Andreas Ioannis Karsisiotis; Christian F Damblon; Gordon C K Roberts
Journal:  Biochem J       Date:  2013-12-15       Impact factor: 3.857
  9 in total

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