Literature DB >> 14982810

Inhibition of beta-lactamase II of Bacillus cereus by penamaldic derivatives of penicillins.

Pilar Gutiérrez Navarro1, Bartolomé Quintero Osso, Raquel García Ortiz, Pedro J Martínez De Las Parras, María I Martínez Puentedura, M Carmen Cabeza González.   

Abstract

The penamaldic derivatives of amoxicillin, ampicillin, and penicillins G and V, stabilized with Zn(2+), were obtained from a methanolic medium. The enzymatic kinetic results show that the these derivatives elicit reversible inhibition of the enzyme metallo-beta-lactamase from Bacillus cereus, with inhibition constant values determined at pH 7.0 and 25 degrees C.

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Year:  2004        PMID： 14982810      PMCID： PMC353088          DOI： 10.1128/AAC.48.3.1058-1060.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.

Authors:  M L Greenlee; J B Laub; J M Balkovec; M L Hammond; G G Hammond; D L Pompliano; J H Epstein-Toney
Journal:  Bioorg Med Chem Lett       Date:  1999-09-06       Impact factor: 2.823

Review 2.  The beta-lactamase cycle: a tale of selective pressure and bacterial ingenuity.

Authors:  A Matagne; A Dubus; M Galleni; J M Frère
Journal:  Nat Prod Rep       Date:  1999-02       Impact factor: 13.423

3.  Interaction between class B beta-lactamases and suicide substrates of active-site serine beta-lactamases.

Authors:  C Prosperi-Meys; G Llabres; D de Seny; R P Soto; M H Valladares; N Laraki; J M Frere; M Galleni
Journal:  FEBS Lett       Date:  1999-01-25       Impact factor: 4.124

4.  The mechanism of catalysis and the inhibition of the Bacillus cereus zinc-dependent beta-lactamase.

Authors:  S Bounaga; A P Laws; M Galleni; M I Page
Journal:  Biochem J       Date:  1998-05-01       Impact factor: 3.857

5.  Carbapenem derivatives as potential inhibitors of various beta-lactamases, including class B metallo-beta-lactamases.

Authors:  R Nagano; Y Adachi; H Imamura; K Yamada; T Hashizume; H Morishima
Journal:  Antimicrob Agents Chemother       Date:  1999-10       Impact factor: 5.191

Review 6.  A functional classification scheme for beta-lactamases and its correlation with molecular structure.

Authors:  K Bush; G A Jacoby; A A Medeiros
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191

7.  Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives.

Authors:  D J Payne; J H Bateson; B C Gasson; D Proctor; T Khushi; T H Farmer; D A Tolson; D Bell; P W Skett; A C Marshall; R Reid; L Ghosez; Y Combret; J Marchand-Brynaert
Journal:  Antimicrob Agents Chemother       Date:  1997-01       Impact factor: 5.191

8.  Inhibition of IMP-1 metallo-beta-lactamase and sensitization of IMP-1-producing bacteria by thioester derivatives.

Authors:  G G Hammond; J L Huber; M L Greenlee; J B Laub; K Young; L L Silver; J M Balkovec; K D Pryor; J K Wu; B Leiting; D L Pompliano; J H Toney
Journal:  FEMS Microbiol Lett       Date:  1999-10-15       Impact factor: 2.742

Review 9.  Metallo-beta-lactamases: a class apart.

Authors:  K Bush
Journal:  Clin Infect Dis       Date:  1998-08       Impact factor: 9.079

10.  Degradation of ampicillin in the presence of cadmium (II) ions.

Authors:  A Márquez García; P Gutiérrez Navarro; P J Martínez de Las Parras
Journal:  Talanta       Date:  1998-05       Impact factor: 6.057
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