Literature DB >> 10471925

Drug screening--beyond the bottleneck.

A Dove.   

Abstract

High-throughput screening still has a long way to go if it is to achieve its often-touted potential.

Mesh:

Year:  1999        PMID: 10471925     DOI: 10.1038/12845

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN: 1087-0156            Impact factor:   54.908


  10 in total

1.  Gaining confidence in high-throughput screening.

Authors:  Jérôme Bibette
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-17       Impact factor: 11.205

Review 2.  Structure-based discovery of antibacterial drugs.

Authors:  Katie J Simmons; Ian Chopra; Colin W G Fishwick
Journal:  Nat Rev Microbiol       Date:  2010-07       Impact factor: 60.633

3.  Advances in Nuclear Magnetic Resonance for Drug Discovery.

Authors:  Robert Powers
Journal:  Expert Opin Drug Discov       Date:  2009-10-01       Impact factor: 6.098

4.  Determining the optimal size of small molecule mixtures for high throughput NMR screening.

Authors:  Kelly A Mercier; Robert Powers
Journal:  J Biomol NMR       Date:  2005-03       Impact factor: 2.835

5.  Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis.

Authors:  Jaime L Stark; Kelly A Mercier; Geoffrey A Mueller; Thomas B Acton; Rong Xiao; Gaetano T Montelione; Robert Powers
Journal:  Proteins       Date:  2010-12

Review 6.  Pooling in high-throughput drug screening.

Authors:  Raghunandan M Kainkaryam; Peter J Woolf
Journal:  Curr Opin Drug Discov Devel       Date:  2009-05

7.  Single-cell analysis and sorting using droplet-based microfluidics.

Authors:  Linas Mazutis; John Gilbert; W Lloyd Ung; David A Weitz; Andrew D Griffiths; John A Heyman
Journal:  Nat Protoc       Date:  2013-04-04       Impact factor: 13.491

8.  The impact of dosing interval in a novel tandem oral dosing strategy: enhancing the exposure of low solubility drug candidates in a preclinical setting.

Authors:  Po-Chang Chiang; Sarah A South; Steve P Wene
Journal:  J Drug Deliv       Date:  2011-01-12

9.  Expression of miRNA-122 Induced by Liver Toxicants in Zebrafish.

Authors:  Hyun-Sik Nam; Kyu-Seok Hwang; Yun-Mi Jeong; Jeong-Im Ryu; Tae-Young Choi; Myung-Ae Bae; Woo-Chan Son; Kwan-Hee You; Hwa-Young Son; Cheol-Hee Kim
Journal:  Biomed Res Int       Date:  2016-08-03       Impact factor: 3.411

Review 10.  Integrating Immunology and Microfluidics for Single Immune Cell Analysis.

Authors:  Nidhi Sinha; Nikita Subedi; Jurjen Tel
Journal:  Front Immunol       Date:  2018-10-16       Impact factor: 7.561

  10 in total

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