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Literature DB >> 10449374

Beyond binding: using phage display to select for structure, folding and enzymatic activity in proteins.

Abstract

Phage display of a wide range of polypeptides has been increasingly used to identify novel molecules with useful binding properties for research, medical and industrial applications. Recent developments include methods for the selection of stabilized variants of a protein, the selection of regulatable enzymes and promising strategies for the selection and evolution of protein catalysts.

Mesh：

Substances：
Enzymes
Peptide Library

Year: 1999 PMID： 10449374 DOI： 10.1016/S0959-440X(99)80073-6

Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809

Keyword Cloud
Cited

19 in total

1. A "loop entropy reduction" phage-display selection for folded amino acid sequences.

Authors: P Minard; M Scalley-Kim; A Watters; D Baker
Journal: Protein Sci Date: 2001-01 Impact factor: 6.725

2. Construction and characterization of protein libraries composed of secondary structure modules.

Authors: Tomoaki Matsuura; Andreas Ernst; Andreas Plückthun
Journal: Protein Sci Date: 2002-11 Impact factor: 6.725

3. Dynamic peptide libraries for the discovery of supramolecular nanomaterials.

Authors: Charalampos G Pappas; Ramim Shafi; Ivan R Sasselli; Henry Siccardi; Tong Wang; Vishal Narang; Rinat Abzalimov; Nadeesha Wijerathne; Rein V Ulijn
Journal: Nat Nanotechnol Date: 2016-10-03 Impact factor: 39.213

4. Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation.

Authors: Feng Wang; Shiladitya Sen; Yong Zhang; Insha Ahmad; Xueyong Zhu; Ian A Wilson; Vaughn V Smider; Thomas J Magliery; Peter G Schultz
Journal: Proc Natl Acad Sci U S A Date: 2013-02-25 Impact factor: 11.205

5. Glycoarrays with engineered phages displaying structurally diverse oligosaccharides enable high-throughput detection of glycan-protein interactions.

Authors: Eda Çelik; Anne A Ollis; Yi Lasanajak; Adam C Fisher; Göksu Gür; David F Smith; Matthew P DeLisa
Journal: Biotechnol J Date: 2014-10-31 Impact factor: 4.677

Beyond binding: using phage display to select for structure, folding and enzymatic activity in proteins.

1. A "loop entropy reduction" phage-display selection for folded amino acid sequences.

2. Construction and characterization of protein libraries composed of secondary structure modules.

3. Dynamic peptide libraries for the discovery of supramolecular nanomaterials.

4. Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation.

5. Glycoarrays with engineered phages displaying structurally diverse oligosaccharides enable high-throughput detection of glycan-protein interactions.

Review 6. Design of virus-based nanomaterials for medicine, biotechnology, and energy.

7. Protein and Antibody Engineering by Phage Display.

Review 8. Carbohydrate binding modules: biochemical properties and novel applications.

9. A filamentous phage display system for N-linked glycoproteins.

10. De novo designed cyclic-peptide heme complexes.