Literature DB >> 10438884

Human papillomavirus type 16 E7 DNA vaccine: mutation in the open reading frame of E7 enhances specific cytotoxic T-lymphocyte induction and antitumor activity.

W Shi1, P Bu, J Liu, A Polack, S Fisher, L Qiao.   

Abstract

A human papillomavirus type 16 E7 DNA vaccine with the open reading frame encoding mutations in two zinc-binding motifs expressed a rapidly degraded E7 protein. This vaccine induced a significantly stronger E7-specific cytotoxic T-lymphocyte response and better tumor protection in mice than did a wild-type E7 DNA vaccine expressing a stable E7 protein.

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Year:  1999        PMID： 10438884      PMCID： PMC104321     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  45 in total

1.  Human papillomavirus type 16 open reading frame E7 encodes a transforming gene for rat 3Y1 cells.

Authors:  T Kanda; A Furuno; K Yoshiike
Journal:  J Virol       Date:  1988-02       Impact factor: 5.103

2.  DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction.

Authors:  F Rodriguez; J Zhang; J L Whitton
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

Review 3.  DNA vaccines.

Authors:  J B Ulmer; J C Sadoff; M A Liu
Journal:  Curr Opin Immunol       Date:  1996-08       Impact factor: 7.486

Review 4.  DNA immunization.

Authors:  D E Hassett; J L Whitton
Journal:  Trends Microbiol       Date:  1996-08       Impact factor: 17.079

Review 5.  DNA vaccines.

Authors:  H L Robinson; C A Torres
Journal:  Semin Immunol       Date:  1997-10       Impact factor: 11.130

6.  E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein.

Authors:  K Herd; G J Fernando; L A Dunn; I H Frazer; P Lambert; R W Tindle
Journal:  Virology       Date:  1997-04-28       Impact factor: 3.616

7.  Suitability of Epstein-Barr virus-based episomal vectors for expression of cytokine genes in human lymphoma cells.

Authors:  S Mũcke; A Polack; M Pawlita; D Zehnpfennig; N Massoudi; H Bohlen; W Doerfler; G Bornkamm; V Diehl; J Wolf
Journal:  Gene Ther       Date:  1997-02       Impact factor: 5.250

Review 8.  Immunology of papillomavirus infection.

Authors:  I H Frazer
Journal:  Curr Opin Immunol       Date:  1996-08       Impact factor: 7.486

9.  Identification of early proteins of the human papilloma viruses type 16 (HPV 16) and type 18 (HPV 18) in cervical carcinoma cells.

Authors:  K Seedorf; T Oltersdorf; G Krämmer; W Röwekamp
Journal:  EMBO J       Date:  1987-01       Impact factor: 11.598

10.  Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization.

Authors:  T W Tobery; R F Siliciano
Journal:  J Exp Med       Date:  1997-03-03       Impact factor: 14.307
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  7 in total

1.  Therapeutic DNA Vaccines for Human Papillomavirus and Associated Diseases.

Authors:  Max A Cheng; Emily Farmer; Claire Huang; John Lin; Chien-Fu Hung; T-C Wu
Journal:  Hum Gene Ther       Date:  2018-03-16       Impact factor: 5.695

2.  Integration of Oncogenes via Sleeping Beauty as a Mouse Model of HPV16+ Oral Tumors and Immunologic Control.

Authors:  Yi-Hsin Lin; Ming-Chieh Yang; Ssu-Hsueh Tseng; Rosie Jiang; Andrew Yang; Emily Farmer; Shiwen Peng; Talia Henkle; Yung-Nien Chang; Chien-Fu Hung; T-C Wu
Journal:  Cancer Immunol Res       Date:  2018-01-23       Impact factor: 11.151

Review 3.  Prevention of cervical cancer with vaccines.

Authors:  S S Im; B J Monk; L P Villarreal
Journal:  Curr Oncol Rep       Date:  2001-07       Impact factor: 5.075

4.  Papillomavirus pseudovirus: a novel vaccine to induce mucosal and systemic cytotoxic T-lymphocyte responses.

Authors:  W Shi; J Liu; Y Huang; L Qiao
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

5.  Targeting HPV-16 antigens to the endoplasmic reticulum induces an endoplasmic reticulum stress response.

Authors:  David H Martínez-Puente; José J Pérez-Trujillo; Yolanda Gutiérrez-Puente; Humberto Rodríguez-Rocha; Aracely García-García; Odila Saucedo-Cárdenas; Roberto Montes-de-Oca-Luna; María J Loera-Arias
Journal:  Cell Stress Chaperones       Date:  2019-01-02       Impact factor: 3.667

6.  Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (shuffling).

Authors:  Fahad N Almajhdi; Tilo Senger; Haitham M Amer; Lutz Gissmann; Peter Öhlschläger
Journal:  PLoS One       Date:  2014-11-25       Impact factor: 3.240

7.  DNA vaccine encoding human papillomavirus antigens flanked by a signal peptide and a KDEL sequence induces a potent therapeutic antitumor effect.

Authors:  Jose J Perez-Trujillo; Rodolfo Garza-Morales; Jose A Barron-Cantu; Gabriel Figueroa-Parra; Aracely Garcia-Garcia; Humberto Rodriguez-Rocha; Jaime Garcia-Juarez; Gerardo E Muñoz-Maldonado; Odila Saucedo-Cardenas; Roberto Montes-De-Oca-Luna; Maria De Jesus Loera-Arias
Journal:  Oncol Lett       Date:  2017-01-23       Impact factor: 2.967
  7 in total

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