Literature DB >> 10425286

Angiogenesis does not correlate with prognosis or expression of vascular endothelial growth factor in synovial sarcomas.

S Kawauchi1, T Fukuda, M Tsuneyoshi.   

Abstract

To investigate the significance of tumour angiogenesis in synovial sarcoma on prognosis, we analysed the correlation between microvessel density (MVD) and various clinicopathological factors or immunohistochemical expression of vascular endothelial growth factor (VEGF) in 54 primary and recurrent synovial sarcomas. MVD in synovial sarcomas did not correlate with prognosis or VEGF expression. Furthermore, VEGF expression in synovial sarcomas did not have any prognostic value on overall survival. Our results indicate that angiogenesis does not play an important role in metastasis of synovial sarcoma and overall survival. Angiogenesis in synovial sarcoma may be controlled by angiogenesis activators other than VEGF.

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Year:  1999        PMID： 10425286     DOI： 10.3892/or.6.5.959

Source DB:  PubMed          Journal:  Oncol Rep        ISSN： 1021-335X            Impact factor:   3.906


  13 in total

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7.  Targeting angiogenesis in childhood sarcomas.

Authors:  Hemant K Bid; Peter J Houghton
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9.  Automatic identification of angiogenesis in double stained images of liver tissue.

Authors:  Mutlu Mete; Leah Hennings; Horace J Spencer; Umit Topaloglu
Journal:  BMC Bioinformatics       Date:  2009-10-08       Impact factor: 3.169

10.  The relationship between lymphatic vascular density and vascular endothelial growth factor A (VEGF-A) expression with clinical-pathological features and survival in pancreatic adenocarcinomas.

Authors:  Verônica A Zorgetto; Giórgia G Silveira; João Paulo Oliveira-Costa; Danilo F Soave; Fernando A Soares; Alfredo Ribeiro-Silva
Journal:  Diagn Pathol       Date:  2013-10-18       Impact factor: 2.644
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