Literature DB >> 10384716

Gold(I) complexes as antimicrobial agents.

F Novelli1, M Recine, F Sparatore, C Juliano.   

Abstract

Seven gold complexes were prepared and investigated for biocidal activity against Gram-positive and -negative bacteria, fungi and protozoa. All of them were active against the tested microorganisms with the exception of Pseudomonas aeruginosa. In many, cases minimum inhibitory concentrations (MIC) were well below 1 microgram/ml. The activity is not simply related to the gold content, but also to the nature of both the phosphine and the aminothiol to which the metal is bound.

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Year:  1999        PMID: 10384716     DOI: 10.1016/s0014-827x(99)00019-1

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  12 in total

1.  Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi.

Authors:  Nathan P Wiederhold; Thomas F Patterson; Anand Srinivasan; Ashok K Chaturvedi; Annette W Fothergill; Floyd L Wormley; Anand K Ramasubramanian; José L Lopez-Ribot
Journal:  Virulence       Date:  2016-06-07       Impact factor: 5.882

2.  Luminescent di- and polynuclear organometallic gold(I)-metal (Au2, {Au2Ag}n and {Au2Cu}n) compounds containing bidentate phosphanes as active antimicrobial agents.

Authors:  Malgorzata Frik; Josefina Jiménez; Ismael Gracia; Larry R Falvello; Sarya Abi-Habib; Karina Suriel; Theodore R Muth; María Contel
Journal:  Chemistry       Date:  2012-02-14       Impact factor: 5.236

3.  Auranofin and related heterometallic gold(I)-thiolates as potent inhibitors of methicillin-resistant Staphylococcus aureus bacterial strains.

Authors:  Yozane Hokai; Boruch Jurkowicz; Jacob Fernández-Gallardo; Nuruddinkodja Zakirkhodjaev; Mercedes Sanaú; Theodore R Muth; María Contel
Journal:  J Inorg Biochem       Date:  2014-05-28       Impact factor: 4.155

4.  Water Soluble Phosphane-Gold(I) Complexes. Applications as Recyclable Catalysts in a Three-component Coupling Reaction and as Antimicrobial and Anticancer Agents.

Authors:  Benelita T Elie; Chaya Levine; Iban Ubarretxena-Belandia; Armando Varela-Ramírez; Renato J Aguilera; Rafael Ovalle; María Contel
Journal:  Eur J Inorg Chem       Date:  2009-06-30       Impact factor: 2.524

5.  The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapy.

Authors:  Vesna Milacic; Q Ping Dou
Journal:  Coord Chem Rev       Date:  2009       Impact factor: 22.315

6.  Group 11 Metal Compounds with Tripodal Bis(imidazole) Thioether Ligands. Applications as Catalysts in the Oxidation of Alkenes and as Antimicrobial Agents.

Authors:  Fangwei Liu; Reema Anis; Eunmi Hwang; Rafael Ovalle; Armando Varela-Ramírez; Renato J Aguilera; María Contel
Journal:  Molecules       Date:  2011-08-08       Impact factor: 4.411

7.  Antibacterial Activity and Cytotoxicity of Gold (I) and (III) Ions and Gold Nanoparticles.

Authors:  T P Shareena Dasari; Y Zhang; H Yu
Journal:  Biochem Pharmacol (Los Angel)       Date:  2015-12-20

8.  The effects of phosphanegold(I) thiolates on the biological properties of Acanthamoeba castellanii belonging to the T4 genotype.

Authors:  Ruqaiyyah Siddiqui; Farhat Abjani; Chien Ing Yeo; Edward R T Tiekink; Naveed Ahmed Khan
Journal:  J Negat Results Biomed       Date:  2017-04-03

Review 9.  Nanoparticles as Anti-Microbial, Anti-Inflammatory, and Remineralizing Agents in Oral Care Cosmetics: A Review of the Current Situation.

Authors:  Florence Carrouel; Stephane Viennot; Livia Ottolenghi; Cedric Gaillard; Denis Bourgeois
Journal:  Nanomaterials (Basel)       Date:  2020-01-13       Impact factor: 5.076

10.  New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates.

Authors:  Dustin Maydaniuk; Bin Wu; Dang Truong; Sajani H Liyanage; Andrew M Hogan; Zhong Ling Yap; Mingdi Yan; Silvia T Cardona
Journal:  Antibiotics (Basel)       Date:  2021-11-24
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