SETTING: Ho Chi Minh City, Vietnam. OBJECTIVE: To evaluate the impact of slide reading errors at peripheral level on case-finding and treatment decisions. DESIGN: Over a 6-month period in 1997, information on date, type of slide, results of other slides from the patient, and treatment status was collected for all slides from district TB centers detected as having reading errors during smear microscopy quality control re-readings. RESULTS: Reading errors were detected in 117 slides: 115 (98.3%) were incorrectly read as negative, and 75 (65.2%) of these errors occurred in case-finding slides. In the 75 falsely negative case-finding slides, re-reading resulted in initiation of treatment in 38 patients (50.7%). The remaining 37 (49.3%) had only one positive slide and were told to return for follow-up after 6 months; the two (5.4%) who did return were both diagnosed with active TB. Detection of errors in the 40 false-negative follow-up slides resulted in treatment changes in four patients (10%). CONCLUSIONS: Quality control plays a critical role in helping to ensure the timely diagnosis and treatment of new TB cases and appropriate management of patients currently on treatment. The usefulness of quality control could be enhanced by focusing greater efforts on case-finding slides initially read as negative.
SETTING: Ho Chi Minh City, Vietnam. OBJECTIVE: To evaluate the impact of slide reading errors at peripheral level on case-finding and treatment decisions. DESIGN: Over a 6-month period in 1997, information on date, type of slide, results of other slides from the patient, and treatment status was collected for all slides from district TB centers detected as having reading errors during smear microscopy quality control re-readings. RESULTS: Reading errors were detected in 117 slides: 115 (98.3%) were incorrectly read as negative, and 75 (65.2%) of these errors occurred in case-finding slides. In the 75 falsely negative case-finding slides, re-reading resulted in initiation of treatment in 38 patients (50.7%). The remaining 37 (49.3%) had only one positive slide and were told to return for follow-up after 6 months; the two (5.4%) who did return were both diagnosed with active TB. Detection of errors in the 40 false-negative follow-up slides resulted in treatment changes in four patients (10%). CONCLUSIONS: Quality control plays a critical role in helping to ensure the timely diagnosis and treatment of new TB cases and appropriate management of patients currently on treatment. The usefulness of quality control could be enhanced by focusing greater efforts on case-finding slides initially read as negative.
Authors: James J Lewis; Violet N Chihota; Minty van der Meulen; P Bernard Fourie; Katherine L Fielding; Alison D Grant; Susan E Dorman; Gavin J Churchyard Journal: PLoS One Date: 2012-11-29 Impact factor: 3.240
Authors: Marleen Vree; Nguyen T Huong; Bui D Duong; Nguyen V Co; Dinh N Sy; Frank G Cobelens; Martien W Borgdorff Journal: BMC Public Health Date: 2007-08-16 Impact factor: 3.295
Authors: Joseph S Cavanaugh; Surbhi Modi; Susan Musau; Kimberly McCarthy; Heather Alexander; Barbara Burmen; Charles M Heilig; Ray W Shiraishi; Kevin Cain Journal: PLoS One Date: 2016-03-29 Impact factor: 3.240