Literature DB >> 1023132

Acid-labile amino acid precursors in the Murchison meteorite. 1: Chromatographic fractionation.

J R Cronin.   

Abstract

The amino acid content of a hot water extract of the Murchison meteorite can be increased by over 100 per cent by subjecting the extract to acid hydrolysis. The acid-labile compounds in the extract that account for this increase were fractionated by column chromatography on a cation exchange resin. Seventy mole per cent behaved as neutral or acidic compounds and were eluted from the column with an initial water wash. The remaining 30 mole per cent (basic precursors) were retained on the column and were eluted with the free amino acids by aqueous NH4OH. The acid-labile amino acid precursors in the water eluate could be retained and further fractionated on an anion exchange column, indicating that they are acidic compounds.

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Year:  1976        PMID: 1023132     DOI: 10.1007/BF00927928

Source DB:  PubMed          Journal:  Orig Life        ISSN: 0302-1688


  7 in total

1.  Nonprotein amino acids in the murchison meteorite.

Authors:  K A Kvenvolden; J G Lawless; C Ponnamperuma
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205

2.  Evidence for compounds hydrolyzable to amino acids in aqueous extracts of apollo 11 and apollo 12 lunar fines.

Authors:  K Harada; P E Hare; C R Windsor; S W Fox
Journal:  Science       Date:  1971-07-30       Impact factor: 47.728

3.  Configuration of amino-acids in carbonaceous chondrites and a Pre-Cambrian chert.

Authors:  J Oro; S Nakaparksin; H Lichtenstein; E Gil-Av
Journal:  Nature       Date:  1971-03-12       Impact factor: 49.962

4.  Amino-acids, aliphatic and aromatic hydrocarbons in the Murchison Meteorite.

Authors:  J Oró; J Gibert; H Lichtenstein; S Wikstrom; D A Flory
Journal:  Nature       Date:  1971-03-12       Impact factor: 49.962

5.  Evidence for extraterrestrial amino-acids and hydrocarbons in the Murchison meteorite.

Authors:  K Kvenvolden; J Lawless; K Pering; E Peterson; J Flores; C Ponnamperuma; I R Kaplan; C Moore
Journal:  Nature       Date:  1970-12-05       Impact factor: 49.962

6.  Amino Acid analyses of the murchison, murray, and allende carbonaceous chondrites.

Authors:  J R Cronin; C B Moore
Journal:  Science       Date:  1971-06-25       Impact factor: 47.728

7.  O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

Authors:  J R Benson; P E Hare
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205

  7 in total
  7 in total

1.  Large enantiomeric excesses in primitive meteorites and the diverse effects of water in cosmochemical evolution.

Authors:  Sandra Pizzarello; Devin L Schrader; Adam A Monroe; Dante S Lauretta
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-09       Impact factor: 11.205

2.  Acid-labile amino acid precursors in the Murchison meteorite. II: A search for peptides and amino acyl amides.

Authors:  J R Cronin
Journal:  Orig Life       Date:  1976-12

3.  Identification of diamino acids in the Murchison meteorite.

Authors:  Uwe J Meierhenrich; Guillermo M Muñoz Caro; Jan Hendrik Bredehöft; Elmar K Jessberger; Wolfram H-P Thiemann
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-11       Impact factor: 11.205

4.  A search for extraterrestrial amino acids in carbonaceous Antarctic micrometeorites.

Authors:  K L Brinton; C Engrand; D P Glavin; J L Bada; M Maurette
Journal:  Orig Life Evol Biosph       Date:  1998-10       Impact factor: 1.950

5.  Dipeptides and diketopiperazines in the Yamato-791198 and Murchison carbonaceous chondrites.

Authors:  Akira Shimoyama; Ryo Ogasawara
Journal:  Orig Life Evol Biosph       Date:  2002-04       Impact factor: 1.950

6.  One-pot synthesis of amino acid precursors with insoluble organic matter in planetesimals with aqueous activity.

Authors:  Yoko Kebukawa; Queenie H S Chan; Shogo Tachibana; Kensei Kobayashi; Michael E Zolensky
Journal:  Sci Adv       Date:  2017-03-17       Impact factor: 14.136

Review 7.  Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones.

Authors:  Danielle N Simkus; José C Aponte; Jamie E Elsila; Eric T Parker; Daniel P Glavin; Jason P Dworkin
Journal:  Life (Basel)       Date:  2019-06-06
  7 in total

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