Literature DB >> 10223960

Synergistic in vitro antimalarial activity of omeprazole and quinine.

T Skinner-Adams1, T M Davis.   

Abstract

Previous studies have shown that the proton pump inhibitor omeprazole has antimalarial activity in vitro. The interactions of omeprazole with commonly used antimalarial drugs were assessed in vitro. Omeprazole and quinine combinations were synergistic; however, chloroquine and omeprazole combinations were antagonistic. Artemisinin drugs had additive antimalarial activities with omeprazole.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10223960      PMCID： PMC89267     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

1.  Chronotherapy of malaria: an approach to malaria chemotherapy.

Authors:  I Landau; A Chabaud; G Cambie; H Ginsburg
Journal:  Parasitol Today       Date:  1991-12

2.  Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment.

Authors:  S Looareesuwan; P Charoenpan; M Ho; N J White; J Karbwang; D Bunnag; T Harinasuta
Journal:  J Infect Dis       Date:  1990-03       Impact factor: 5.226

3.  Interactions of atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro.

Authors:  C J Canfield; M Pudney; W E Gutteridge
Journal:  Exp Parasitol       Date:  1995-05       Impact factor: 2.011

4.  Dose factor of potentiation derived from isoboles.

Authors:  G Pöch
Journal:  Arzneimittelforschung       Date:  1980

5.  A method for testing for synergy with any number of agents.

Authors:  M C Berenbaum
Journal:  J Infect Dis       Date:  1978-02       Impact factor: 5.226

Review 6.  Omeprazole (Prilosec).

Authors:  C Hochwald; E Farrington
Journal:  Pediatr Nurs       Date:  1996 Sep-Oct

7.  Human malaria parasites in continuous culture.

Authors:  W Trager; J B Jensen
Journal:  Science       Date:  1976-08-20       Impact factor: 47.728

8.  Pharmacokinetics of intravenous omeprazole in children.

Authors:  E Jacqz-Aigrain; M Bellaich; C Faure; J Andre; P Rohrlich; V Baudouin; J Navarro
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

9.  Purification of Plasmodium falciparum digestive vacuoles and partial characterization of the vacuolar membrane ATPase.

Authors:  I Choi; J L Mego
Journal:  Mol Biochem Parasitol       Date:  1988-10       Impact factor: 1.759

Review 10.  Omeprazole. An update of its pharmacology and therapeutic use in acid-related disorders.

Authors:  M I Wilde; D McTavish
Journal:  Drugs       Date:  1994-07       Impact factor: 9.546
View more
  8 in total

1.  Efficacy of proton pump inhibitor drugs against Plasmodium falciparum in vitro and their probable pharmacophores.

Authors:  Michael A Riel; Dennis E Kyle; Apurba K Bhattacharjee; Wilbur K Milhous
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

2.  In vitro interactions between piperaquine, dihydroartemisinin, and other conventional and novel antimalarial drugs.

Authors:  Timothy M E Davis; Juliana Hamzah; Kenneth F Ilett; Harin A Karunajeewa; John C Reeder; Kevin T Batty; Sara Hackett; P Hugh R Barrett
Journal:  Antimicrob Agents Chemother       Date:  2006-08       Impact factor: 5.191

Review 3.  Acid-Suppressive Therapy and Risk of Infections: Pros and Cons.

Authors:  Leon Fisher; Alexander Fisher
Journal:  Clin Drug Investig       Date:  2017-07       Impact factor: 2.859

4.  Gametocytocidal activity and synergistic interactions of riboflavin with standard antimalarial drugs against growth of Plasmodium falciparum in vitro.

Authors:  T Akompong; S Eksi; K Williamson; K Haldar
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

5.  Saquinavir inhibits the malaria parasite's chloroquine resistance transporter.

Authors:  Rowena E Martin; Alice S Butterworth; Donald L Gardiner; Kiaran Kirk; James S McCarthy; Tina S Skinner-Adams
Journal:  Antimicrob Agents Chemother       Date:  2012-02-21       Impact factor: 5.191

6.  Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum.

Authors:  Donelly A van Schalkwyk; Benjamin Blasco; Rocio Davina Nuñez; Jonathan W K Liew; Amirah Amir; Yee L Lau; Didier Leroy; Robert W Moon; Colin J Sutherland
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2019-02-22       Impact factor: 4.077

7.  Is it possible to use Proton Pump Inhibitors in COVID-19 treatment and prophylaxis?

Authors:  Şeyma Taştemur; Hilmi Ataseven
Journal:  Med Hypotheses       Date:  2020-06-20       Impact factor: 1.538

8.  Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms.

Authors:  Giulliana T Almeida; Regina C G Lage; Leticia Anderson; Thiago M Venancio; Helder I Nakaya; Patrícia A Miyasato; Henrique K Rofatto; Adhemar Zerlotini; Eliana Nakano; Guilherme Oliveira; Sergio Verjovski-Almeida
Journal:  PLoS Negl Trop Dis       Date:  2015-09-24
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.