| Literature DB >> 2179427 |
S Looareesuwan1, P Charoenpan, M Ho, N J White, J Karbwang, D Bunnag, T Harinasuta.
Abstract
A 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria.Entities:
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Year: 1990 PMID： 2179427 DOI： 10.1093/infdis/161.3.577
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226